2. Others
  3. Fluorescent Dye
  4. DCI-Br-3

DCI-Br-3 是一种快速、高灵敏度和选择性的检测癫痫脑硫醇的探针。(λex=537 nm，λem=675 nm)。DCI-Br-3 能有效跨越血脑屏障 (BBB)。

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DCI-Br-3 Chemical Structure

DCI-Br-3 Chemical Structure

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DCI-Br-3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DCI-Br-3 is a rapid, highly sensitive, and selective probe to monitor thiols in the epileptic brain. (λex=537 nm, λem=675 nm).DCI-Br-3 can effectively cross the blood-brain barrier (BBB)[1].

体外研究
(In Vitro)

DCI-Br-3 (0-20 μM; 30 min; SH-SY5Y cells) increases intracellular fluorescence in a concentration-dependent manner and has a good response to thiols in SH-SY5Y cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DCI-Br-3 相关抗体:
体内研究
(In Vivo)

DCI-Br-3 (5 mg/kg; i.p.; BALB/c mice) effectively crosses the blood-brain barrier and help monitor the decrease of thiols in the brain[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: BALB/c mice (6 weeks of age)[1]
Dosage: 5 mg/kg
Administration: intraperitoneal injection
Result: Crossed the blood−brain barrier and had red fluorescence in BALB/c mice.
分子量

474.35

Formula

C25H20BrN3O2
Emission (Em)

675
Excitation (Ex)

537
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DCI-Br-3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DCI-Br-3Fluorescent Dyethiolsblood-brain barrierSH-SY5Y cellredInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-151615
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