1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. DL-β-Hydroxybutyryl coenzyme A lithium

DL-β-Hydroxybutyryl coenzyme A lithium 

目录号: HY-134426 纯度: ≥98.0%
COA 产品使用指南

DL-β-Hydroxybutyryl coenzyme A lithium 是丁酸发酵以及赖氨酸和色氨酸代谢的中间体,由 β-羟基丁酸通过短链-CoA 合成酶生成。

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DL-β-Hydroxybutyryl coenzyme A lithium Chemical Structure

DL-β-Hydroxybutyryl coenzyme A lithium Chemical Structure

CAS No. : 103404-51-9

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1 mg ¥1800
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Other Forms of DL-β-Hydroxybutyryl coenzyme A lithium:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DL-β-Hydroxybutyryl coenzyme A lithium is an intermediate in the fermentation of butyric acid and the metabolism of lysine and tryptophan, and is produced from β-hydroxybutyric acid by short-chain-CoA synthase[1][2].

体外研究
(In Vitro)

DL-β-Hydroxybutyryl coenzyme A lithium (β-Hydroxybutyryl-CoA) can be produced as an intermediate metabolite via the mitochondrial pathway, where impaired mitochondrial function in cancer cells leads to the accumulation of it. At the same time, DL-β-Hydroxybutyryl coenzyme A lithium can also be produced via the fatty acid β-oxidation, which is accelerated by starvation and fasting, leading to the accumulation of it and thus to diseases caused by certain metabolic adaptations[1].
DL-β-Hydroxybutyryl coenzyme A lithium (β-Hydroxybutyryl-CoA) can act as a cofactor for lysine β-hydroxybutyrylation (Kbhb), with elevated levels of histone Kbhb in a streptozotocin (STZ)-induced type 1 diabetes mellitus (T1DM) mouse model[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

874.45

Formula

C25H42Li3N7O18P3S

CAS 号
性状

固体

颜色

White to off-white

初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验: 

H2O 中的溶解度 : 50 mg/mL (57.18 mM; 超声加热助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.1436 mL 5.7179 mL 11.4358 mL
5 mM 0.2287 mL 1.1436 mL 2.2872 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度,如有需要,请与 MCE 中国技术支持联系。
纯度 & 产品资料

纯度: ≥98.0%

参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.1436 mL 5.7179 mL 11.4358 mL 28.5894 mL
5 mM 0.2287 mL 1.1436 mL 2.2872 mL 5.7179 mL
10 mM 0.1144 mL 0.5718 mL 1.1436 mL 2.8589 mL
15 mM 0.0762 mL 0.3812 mL 0.7624 mL 1.9060 mL
20 mM 0.0572 mL 0.2859 mL 0.5718 mL 1.4295 mL
25 mM 0.0457 mL 0.2287 mL 0.4574 mL 1.1436 mL
30 mM 0.0381 mL 0.1906 mL 0.3812 mL 0.9530 mL
40 mM 0.0286 mL 0.1429 mL 0.2859 mL 0.7147 mL
50 mM 0.0229 mL 0.1144 mL 0.2287 mL 0.5718 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
DL-β-Hydroxybutyryl coenzyme A lithium
目录号:
HY-134426
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