2. Cell Cycle/DNA Damage
  3. Eukaryotic Initiation Factor (eIF)
  4. DMDA-PatA

DMDA-PatA 是一种小分子 eIF4A 抑制剂，能够通过将 eIF4A (一种 DEAD-box RNA 结合蛋白) 以一种 mRNA 选择性且与 ATP 无关的方式夹紧到 GNG 基序上，抑制翻译。DMDA-PatA 有望用于癌症和病毒感染的研究。

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DMDA-PatA Chemical Structure

DMDA-PatA Chemical Structure

CAS No. : 1531593-48-2

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DMDA-PatA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DMDA-PatA is a small-molecule eIF4A inhibitor that represses translation in an mRNA-selective and ATP-independent manner by clamping eIF4A, a DEAD-box RNA binding protein, onto GNG motifs. DMDA-PatA is promising for research of cancers and viral infections[1].

IC50 & Target

eIF4

 

分子量

526.73

Formula

C30H42N2O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DMDA-PatA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DMDA-PatA1531593-48-2Eukaryotic Initiation Factor (eIF)eIF4AtranslationGNG motifscancersviral infectionsInhibitorinhibitorinhibit

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产品名称：
DMDA-PatA
目录号：
HY-169123
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