2. Epigenetics
  3. DNA Methyltransferase
  4. DNMT-IN-1

DNMT-IN-1 是一种有效的 DNMT 抑制剂，EC50 值为 3.2 µM。DNMT-IN-1 具有抗增殖活性。

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DNMT-IN-1 Chemical Structure

DNMT-IN-1 Chemical Structure

CAS No. : 2396691-28-2

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DNMT-IN-1 相关抗体

Top Publications Citing Use of Products

查看 DNA Methyltransferase 亚型特异性产品:

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DNA Methyltransferase DNMT1 DNMT3 MGMT

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DNMT-IN-1 is a potent DNMT inhibitor with an EC50 value of 3.2 µM. DNMT-IN-1 shows antiproliferative active[1].

IC50 & Target[1]

DNA Methyltransferase

3.2 μM (EC50)

体外研究
(In Vitro)

DNMT-IN-1 (compound 3b) 具有抗增殖活性，对 KG1、HCT116 细胞的 EC50 分别为 13.0、10.7 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

DNMT-IN-1 相关抗体:

Cell Proliferation Assay[1]

Cell Line: KG1, HCT116 cells
Concentration: 0-100 µM
Incubation Time: 72 h
Result: Showed antiproliferative active with EC50s of 13.0, 10.7 µM for KG1, HCT116 cells, respectively.
分子量

393.15

Formula

C15H9BrN2O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DNMT-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DNMT-IN-12396691-28-2DNA MethyltransferaseDNMTsDNA MTasesKG1HCT116 cellsantiproliferativeluciferase reexpressionInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-133030
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