2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. DuP 747 hydrochloride

DuP 747 hydrochloride是一种镇痛药，具有选择性kappa-阿片受体激动剂活性。DuP 747在SC给药时表现出较少的spiradoline适宜的选择，但在IP或PO给药时，表现出部分对spiradoline的广泛化反应。DuP 747的5-羟基-去甲氧基代谢物仅诱发选择生理盐水适宜杠杆。DuP 747的作用提示其代谢物可能在IP和PO给药后的spiradoline类似反应中起主要作用。

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DuP 747 hydrochloride Chemical Structure

DuP 747 hydrochloride Chemical Structure

CAS No. : 115904-74-0

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Other Forms of DuP 747 hydrochloride:

DuP 747 hydrochloride 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

DuP 747 hydrochloride is an analgesic with selective kappa-opioid receptor agonist activity. DuP 747 showed less spiradoline-appropriate selection when administered SC, but showed a partial generalized response to spiradoline when administered IP or PO. The 5-hydroxy-desmethoxy metabolite of DuP 747 induced selection of the saline-appropriate lever only. The effects of DuP 747 suggest that its metabolites may play a major role in the similar responses to spiradoline after IP and PO administration[1].

分子量

483.86

Formula

C24H29Cl3N2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

DuP 747 hydrochloride 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DuP 747115904-74-0DuP747DuP-747Opioid ReceptorInhibitorinhibitorinhibit

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产品名称：
DuP 747 hydrochloride
目录号：
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