2. Protein Tyrosine Kinase/RTK
  3. DYRK
  4. Dyrk1A/α-synuclein-IN-1

Dyrk1A/α-synuclein-IN-1 (Compound b1) 是一种 Dyrk1A 和 α-synuclein aggregation 双重抑制剂，IC50 值分别为 177 nM 和 10.5 µM。Dyrk1A/α-synuclein-IN-1 具有较高的预测 CNS 渗透性和神经保护效果。

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Dyrk1A/α-synuclein-IN-1 Chemical Structure

Dyrk1A/α-synuclein-IN-1 Chemical Structure

CAS No. : 2789711-47-1

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Dyrk1A/α-synuclein-IN-1 相关抗体

Top Publications Citing Use of Products

查看 DYRK 亚型特异性产品:

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DYRK1 DYRK2 DYRK3 DYRK4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual Dyrk1A and α-synuclein aggregation inhibitor with IC50 values of 177 nM and 10.5 µM, respectively. Dyrk1A/α-synuclein-IN-1 has high predictive CNS penetration and neuroprotective effect[1].

IC50 & Target

DYRK1A

177 nM (IC50)

α-synuclein aggregation

10.5 μM (IC50)

分子量

411.48

Formula

C20H21N5O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dyrk1A/α-synuclein-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dyrk1A/α-synuclein-IN-12789711-47-1DYRKDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseSH-SY5YParkinson’s diseaseneuroprotectiveCNS penetrationInhibitorinhibitorinhibit

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产品名称：
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目录号：
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