DYRK Inhibitors

DYRK1

DYRK2

DYRK3

DYRK4

DYRK Inhibitors

Product Name	DYRK1	DYRK2	DYRK3	DYRK4	Purity
Harmine	DYRK1A				99.88%
AZ191	DYRK1B				99.98%
GSK-626616	DYRK1	DYRK2	DYRK3		99.77%
T025	DYRK1A, Kd: 0.074 nM DYRK1B, Kd: 1.5 nM	DYRK2, Kd: 32 nM			98.84%
Dyrk1A-IN-11	DYRK1A, EC₅₀: 0.0021 μM
hAChE-IN-8	DYRK1A, IC₅₀: >10 μM
YK-2-69		DYRK2, IC₅₀: 9 nM
DYRK1-IN-1	DYRK1A, IC₅₀: 220 nM DYRK1A, Kd: 3 nM DYRK1B, Kd: 56 nM				99.71%
EHT 1610	DYRK1A DYRK1B				98.16%
Protein kinase inhibitor 1 hydrochloride	DYRK1	DYRK2			≥98.0%
GNF2133	DYRK1A, IC₅₀: 0.0062 μM				98.49%
ML167	DYRK1A, IC₅₀: ＞10000 nM DYRK1B, IC₅₀: 4420 nM				98.62%
RO5454948	DYRK1				99.53%
INDY	DYRK1A DYRK1B				99.51%
ILK-IN-3	DYRK1				99.62%
Dyrk1A-IN-5	DYRK1A, IC₅₀: 6 nM DYRK1B, IC₅₀: 600 nM	DYRK2, IC₅₀: >10000 nM			98.56%
AZ-Dyrk1B-33	DYRK1B				99.95%
Harmine hydrochloride	DYRK1A				99.93%
EHT 5372	DYRK1A, IC₅₀: 0.22 nM DYRK1B, IC₅₀: 0.28 nM	DYRK2, IC₅₀: 10.8 nM		DYRK4, IC₅₀: 93.2 nM	98.12%
GNF4877	DYRK1A, IC₅₀: 6 nM				99.41%
Dyrk1A-IN-4	DYRK1A, IC₅₀: 2 nM	DYRK2, IC₅₀: 6 nM			99.90%
LDN-192960 hydrochloride	DYRK1	DYRK2			99.78%
KH-CB20	DYRK1A, IC₅₀: 57.8 nM				99.80%
CLK1-IN-3	DYRK1A, IC₅₀: 1521 nM				98.03%
ON 108600	DYRK1A, IC₅₀: 0.016 μM DYRK1B, IC₅₀: 0.007 μM	DYRK2, IC₅₀: 0.028 μM			99.73%
DYRKs-IN-1 hydrochloride	DYRK1A, IC₅₀: 5 nM DYRK1B, IC₅₀: 8 nM				99.71%
HTH-01-091				DYRK4, IC₅₀: 41.8 nM	98.64%
(R)-(+)-O-Demethylbuchenavianine	DYRK1A				98.67%
DYRKs-IN-1	DYRK1A, IC₅₀: 5 nM DYRK1B, IC₅₀: 8 nM
MBM-55S	DYRK1A, IC₅₀: 6.5 nM
Dyrk1A/α-synuclein-IN-2	DYRK1A
Haspin-IN-2	DYRK1A, IC₅₀: 917 nM
Dyrk1A-IN-7	DYRK1A, IC₅₀: 28 nM
Dyrk1A-IN-8	DYRK1A, IC₅₀: 209 nM
Dyrk1A/B-IN-1	DYRK1A, Ki: 67.8 nM DYRK1B, Ki: 237.9 nM
Haspin-IN-1	DYRK1A, IC₅₀: 916.3 nM
Dyrk1A-IN-1	DYRK1
JH-XVII-10	DYRK1A, IC₅₀: 3 nM DYRK1B, IC₅₀: 5 nM
Dyrk1A-IN-2	DYRK1A, EC₅₀: 37 nM
GNF2133 hydrochloride	DYRK1A, IC₅₀: 0.0062 μM
JH-XIV-68-3	DYRK1
ZJCK-6-46	DYRK1A, IC₅₀: 0.68 nM DYRK1B, IC₅₀: 1.02 nM	DYRK2, IC₅₀: 14.18 nM	DYRK3, IC₅₀: 17.48 nM	DYRK4, IC₅₀: 401.3 nM
Dyrk1A/α-synuclein-IN-1	DYRK1A, IC₅₀: 177 nM

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