2. Protein Tyrosine Kinase/RTK Anti-infection
  3. DYRK Enterovirus
  4. Dyrk1A-IN-12

Dyrk1A-IN-12 (compound S43) 是一种双特异性酪氨酸磷酸化调节激酶 1A (Dyrk (Dual specificity tyrosine phosphorylation regulated kinase 1A) 抑制剂。Dyrk1A-IN-12 抑制 Dyrk1A 的 IC50 为 95 nM。Dyrk1A-IN-12 显示出抗 EV-A71 (肠道病毒 A71) 活性，其 EC50 为 4.4 μM，CC50 为 12.8 μM，SI 为2.9。Dyrk1A-IN-12 对单纯疱疹病毒 (HSV) 也表现出强效抑制作用。

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Dyrk1A-IN-12 Chemical Structure

Dyrk1A-IN-12 Chemical Structure

CAS No. : 2243701-11-1

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Dyrk1A-IN-12 相关抗体

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查看 DYRK 亚型特异性产品:

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DYRK1 DYRK2 DYRK3 DYRK4

  • 生物活性

  • 纯度 & 产品资料

生物活性

Dyrk1A-IN-12 (compound S43) is a Dyrk (Dual specificity tyrosine phosphorylation regulated kinase 1A inhibitor. Dyrk1A-IN-12 inhibits Dyrk1A with a IC50 of 95 nM. Dyrk1A-IN-12 shows anti-EV-A71 activity with an EC50 of 4.4 μM, CC50 of 12.8 μM and SI of 2.9. Dyrk1A-IN-12 shows potent inhibition against herpes simplex virus (HSV)[1].

IC50 & Target[1]

DYRK1A

95 nM (IC50)

分子量

405.44

Formula

C22H16FN3O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Dyrk1A-IN-12 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dyrk1A-IN-122243701-11-1DYRKEnterovirusDual specificity tyrosine phosphorylation regulated kinaseDual specificity tyrosine regulated kinaseRhinovirusHRVHRVsHEVHEVsEnteroviruses2,4-Disubstituted thiopheneNeurological complicationsInhibitorinhibitorinhibit

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