EPQpYEEIPIYL 

EPQpYEEIPIYL, a phosphopeptide, is a Src homology 2 (SH2) domain ligand. EPQpYEEIPIYL activates Src family members (e.g. Lck, Hck, Fyn) by binding to SH2 domains^[1][2].

pY324，是一种 hmT 衍生的磷酸肽，序列为 EPQpYEEIPIYL，显示出与 Lck SH2 结构域的 GST 融合蛋白(比 Lck 对 Lck 尾部磷酸肽的亲和力高 5 倍) 和 Src SH2 结构域的高亲和力结合 (对Src尾部磷酸肽的亲和力比Src高44倍)^[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

1473.52

C₆₆H₉₇N₁₂O₂₄P

147612-86-0

固体

White to off-white

EPQpYEEIPIYL

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

• [1]. G Payne, et al. The phosphopeptide-binding specificity of Src family SH2 domains. Chem Biol. 1994 Oct;1(2):99-105.  [Content Brief]

  [2]. T D Mulhern, et al. The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity. Structure. 1997 Oct 15;5(10):1313-23.  [Content Brief]