2. Metabolic Enzyme/Protease Apoptosis GPCR/G Protein MAPK/ERK Pathway
  3. Farnesyl Transferase Apoptosis Ras
  4. FTI-277 TFA

FTI-277 TFA 是法尼基转移酶 FTase 抑制剂，高效 Ras CAAX 肽模拟物，可抑制 H-Ras 和 K-Ras 信号转导。FTI-277 TFA 可抑制 hepatitis delta virus (HDV) 感染。

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FTI-277 TFA Chemical Structure

FTI-277 TFA Chemical Structure

CAS No. : 1217447-06-7

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Other Forms of FTI-277 TFA:

FTI-277 TFA 相关抗体

Top Publications Citing Use of Products

    FTI-277 TFA purchased from MCE. Usage Cited in: Oncotarget. 2017 Nov 22;8(65):109135-109150.  [Abstract]

    MCF-7 cells are pretreated with the indicated chemical inhibitors for 30min, followed by 15 min treatment with RA (20 μM) + EPA (80 μM).Cell extracts are prepared and subjected to western blotting analysis.

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    K-Ras H-Ras N-Ras Ras

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    FTI-277 TFA is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. FTI-277 TFA can inhibit hepatitis delta virus (HDV) infection.

    分子量

    561.64

    Formula

    C24H30F3N3O5S2
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    FTI-277 TFA 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    FTI-2771217447-06-7FTI277FTI 277Farnesyl TransferaseApoptosisRasFtaseInhibitorinhibitorinhibit

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    产品名称：
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    目录号：
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