1. Metabolic Enzyme/Protease Apoptosis GPCR/G Protein MAPK/ERK Pathway
  2. Farnesyl Transferase Apoptosis Ras
  3. FTI-277 TFA

FTI-277 TFA 是法尼基转移酶 FTase 抑制剂,高效 Ras CAAX 肽模拟物,可抑制 H-RasK-Ras 信号转导。FTI-277 TFA 可抑制 hepatitis delta virus (HDV) 感染。

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FTI-277 TFA Chemical Structure

FTI-277 TFA Chemical Structure

CAS No. : 1217447-06-7

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    FTI-277 TFA purchased from MCE. Usage Cited in: Oncotarget. 2017 Nov 22;8(65):109135-109150.  [Abstract]

    MCF-7 cells are pretreated with the indicated chemical inhibitors for 30min, followed by 15 min treatment with RA (20 μM) + EPA (80 μM).Cell extracts are prepared and subjected to western blotting analysis.

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    生物活性

    FTI-277 TFA is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. FTI-277 TFA can inhibit hepatitis delta virus (HDV) infection.

    分子量

    561.64

    Formula

    C24H30F3N3O5S2

    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.

    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.

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    参考文献
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    产品名称:
    FTI-277 TFA
    目录号:
    HY-110038
    需求量: