CHST4 - carbohydrate sulfotransferase 4 Gene

中文名称：碳水化合物磺基转移酶 4

种属: Homo sapiens

同用名: GST3; LSST; GlcNAc6ST2; HECGLCNAC6ST

关于 CHST4

功能概要

该基因编码 N-乙酰葡糖胺 6-O 磺基转移酶。编码的酶将硫酸盐从 3' 磷酸腺苷 5' 磷酸硫酸盐转移到糖蛋白上 N-乙酰葡糖胺的 6-羟基。该蛋白质定位于高尔基体，并参与淋巴细胞归巢受体 L-选择素配体上聚糖结构的修饰。 5' UTR 中的交替剪接导致编码相同蛋白质的多个转录变体。[RefSeq 提供，2009 年 10 月]

This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded Enzyme transfers sulfate from 3'phosphoadenosine 5'phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]