1. Gene
  2. ECD - ecdysoneless cell cycle regulator Gene

ECD - ecdysoneless cell cycle regulator Gene

中文名称:无蜕皮激素细胞周期调节因子

种属: Homo sapiens

同用名: GCR2; SGT1; HSGT1

基因 ID: 11319 | 基因类型: protein coding

关于 ECD

Cytogenetic location: 10q22.2 Genomic coordinates (GRCh38): 10:73,133,668-73,168,095 (from NCBI)

This gene has 8 transcripts (splice variants) and 207 orthologues. Ubiquitous expression in testis (RPKM 14.0), thyroid (RPKM 12.4) and 25 other tissues.

功能概要

启用组蛋白乙酰转移酶结合活性。参与 RNA 聚合酶 II 对转录的正调控。位于细胞质和核质中。 [由基因组资源联盟提供,2022 年 4 月]

Enables Histone Acetyltransferase binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ECD 基因产物(3)

mRNA Protein Name
NM_001135752.1 NP_001129224.1 protein ecdysoneless homolog isoform 2
NM_001135753.1 NP_001129225.1 protein ecdysoneless homolog isoform 3
NM_007265.3 NP_009196.1 protein ecdysoneless homolog isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone acetyltransferase binding IDA
IDA: 通过直接分析推断
19919181 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
23880345 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19919181 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
19919181 GOA
located in nucleus IDA
IDA: 通过直接分析推断
19919181 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ECD 蛋白结构

SGT1

SGT1: SGT1 protein (13 - 597)

  • 0
  • 100
  • 200
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  • 500
  • 600
  • 644 a.a.
蛋白主名 其他名称

protein ecdysoneless homolog

ecdysoneless homolog

重组 ECD 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74182 ECD Protein, Human (sf9, His-GST) O95905-1 (M1-N644) ≥95%

关联疾病

疾病名称 别名
Cerebral Primitive Neuroectodermal Tumor

Pnet Of Cerebrum

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ECD VGNC VGNC:71852
Rattus norvegicus ECD RGD RGD:1565023
Canis familiaris ECD VGNC VGNC:40180
Felis catus ECD VGNC VGNC:61706
Bos taurus ECD VGNC VGNC:28301
Mus musculus ECD MGD MGI:1917851
Macaca fascicularis ECD NCBI NCBI:102129143
Others ECD NCBI