1. Gene
  2. Car4 - carbonic anhydrase 4 Gene

Car4 - carbonic anhydrase 4 Gene

中文名称:碳酸酐酶 4

种属: Mus musculus

同用名: Ca4

基因 ID: 12351 | 基因类型: protein coding

关于 Car4

Chromosome 11: 84,848,612-84,856,870 forward strand.GRCm39:CM001004.3

This gene has 6 transcripts (splice variants), 333 orthologues, 15 paralogues and is associated with 9 phenotypes. Biased expression in colon adult (RPKM 148.4), placenta adult (RPKM 86.4) and 1 other tissues.

功能概要

该基因编码的蛋白可启动碳酸盐脱水酶活性。预计参与碳酸氢盐运输和一碳代谢过程。预计在二氧化碳运输和 pH 调节的上游或内部起作用。位于膜内。是质膜的锚定成分。在心血管系统中表达;泌尿生殖系统;神经系统;和尾巴。该基因的人类直系同源物与色素性视网膜炎有关。与人 CA4(碳酸酐酶 4)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables carbonate dehydratase activity. Predicted to be involved in bicarbonate transport and one-carbon metabolic process. Predicted to act upstream of or within carbon dioxide transport and regulation of pH. Located in membrane. Is anchored component of plasma membrane. Is expressed in cardiovascular system; genitourinary system; nervous system; and tail. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Orthologous to human CA4 (Carbonic Anhydrase 4). [provided by Alliance of Genome Resources, Apr 2022]

Car4 基因产物(1)

mRNA Protein Name
NM_007607.2 NP_031633.1 carbonic anhydrase 4 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carbonate dehydratase activity IDA
IDA: 通过直接分析推断
14660577 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
14567693 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
16083424 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16083424 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Car4 蛋白结构

alpha_CA_IV_XV_like

alpha_CA_IV_XV_like: cd03117 (47 - 275)

  • 0
  • 100
  • 200
  • 305 a.a.
蛋白主名 其他名称

carbonic anhydrase 4

CA-IV

carbonate dehydratase IV

carbonic anhydrase IV

重组 Car4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7717 Carbonic Anhydrase 4 Protein, Mouse (HEK293, His) Q64444 (E18-S277) ≥95%