2. Gene
  3. LTB4R - leukotriene B4 receptor Gene

LTB4R - leukotriene B4 receptor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：白三烯 B4 受体

种属: Homo sapiens

同用名: BLT1; BLTR; P2Y7; GPR16; LTBR1; P2RY7; CMKRL1; LTB4R1

基因 ID: 1241 | 基因类型: protein coding

关于 LTB4R

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,311,502-24,318,036 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 141 orthologues and 17 paralogues. Biased expression in skin (RPKM 33.9), esophagus (RPKM 9.6) and 10 other tissues.

功能概要

预计可启用 G 蛋白偶联肽受体活性和白三烯 B4 受体活性。预计参与炎症反应和神经肽信号通路。预测作用于信号转导的上游或内部。预测位于质膜中。预计是质膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled peptide receptor activity and leukotriene B4 receptor activity. Predicted to be involved in inflammatory response and neuropeptide signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LTB4R 基因产物(2)

mRNA Protein Name
NM_001143919.3 NP_001137391.1 leukotriene B4 receptor 1
NM_181657.3 NP_858043.1 leukotriene B4 receptor 1

LTB4R 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (35 - 285)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
蛋白主名 其他名称

leukotriene B4 receptor 1

G protein-coupled receptor 16

LTB4-R 1

LTB4-R1

P2Y purinoceptor 7

chemoattractant receptor-like 1

chemokine receptor-like 1

purinergic receptor P2Y, G-protein coupled, 7

关联疾病

疾病名称 别名
Entropion
Trichomoniasis

Trichomonas Infection

Trichomonas Infections

Disease Due To Trichomonadidae

Infection By Trichomonas

Trichomonadosis

Trichomonas Pruritus

Trichomonosis

Tricomoniasis
Psoriasis 5

PSORS5

Psoriasis Susceptibility 5

Psoriasis 5, Susceptibility To
Persistent Mild Asthma
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus
Dirofilariasis

Dirofilaria Infectious Disease

Infection By Dirofilaria
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07873 LTB4R Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07874 Ltb4r Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07875 Ltb4r1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS07876 LTB4R2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LTB4R RGD RGD:620410
Macaca mulatta LTB4R VGNC VGNC:74455
Felis catus LTB4R VGNC VGNC:68102
Mus musculus LTB4R MGD MGI:1309472
Bos taurus LTB4R VGNC VGNC:31069
Canis familiaris LTB4R VGNC VGNC:42855
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