1. Gene
  2. UBE2F - ubiquitin conjugating enzyme E2 F (putative) Gene

UBE2F - ubiquitin conjugating enzyme E2 F (putative) Gene

中文名称:泛素结合酶 E2 F (假定)

种属: Homo sapiens

同用名: NCE2

基因 ID: 140739 | 基因类型: protein coding

关于 UBE2F

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:237,967,014-238,042,782 (from NCBI)

This gene has 23 transcripts (splice variants), 234 orthologues and 24 paralogues. Ubiquitous expression in bone marrow (RPKM 11.8), thyroid (RPKM 10.6) and 25 other tissues.

功能概要

启用 NEDD8 结合酶活性。参与蛋白质 neddylation。预测位于胞质溶胶中。预计活跃于核心。 [由基因组资源联盟提供,2022 年 4 月]

Enables NEDD8 conjugating Enzyme activity. Involved in protein neddylation. Predicted to be located in cytosol. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

UBE2F 基因产物(5)

mRNA Protein Name
NM_001278305.2 NP_001265234.1 NEDD8-conjugating enzyme UBE2F isoform 1
NM_001278306.2 NP_001265235.1 NEDD8-conjugating enzyme UBE2F isoform 2
NM_001278307.2 NP_001265236.1 NEDD8-conjugating enzyme UBE2F isoform 3
NM_001278308.2 NP_001265237.1 NEDD8-conjugating enzyme UBE2F isoform 4
NM_080678.3 NP_542409.1 NEDD8-conjugating enzyme UBE2F isoform 1

UBE2F 蛋白结构

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (37 - 179)

  • 0
  • 100
  • 185 a.a.
蛋白主名 其他名称

NEDD8-conjugating enzyme UBE2F

NEDD8 carrier protein UBE2F

重组 UBE2F 蛋白

目录号 产品名 蛋白编号 纯度
HY-P79452 UBE2N/Ubc13 Protein, Human (sf9, His, Strep) P61088 (A2-I152) ≥95%

关联疾病

疾病名称 别名
Brachydactyly, Type E2

Brachydactyly Type E2

BDE2

Brachydactyly E2

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus UBE2F VGNC VGNC:55693
Rattus norvegicus UBE2F RGD RGD:1307608
Felis catus UBE2F VGNC VGNC:80398
Mus musculus UBE2F MGD MGI:1915171
Canis familiaris UBE2F VGNC VGNC:59099
Macaca mulatta UBE2F VGNC VGNC:104562
Others UBE2F NCBI