1. Gene
  2. Cygb - cytoglobin Gene

Cygb - cytoglobin Gene

种属: Rattus norvegicus

同用名: Glnf; Stap; Staap

基因 ID: 170520 | 基因类型: protein coding

关于 Cygb

功能概要

Enables catalase activity; fatty acid peroxidase activity; and heme binding activity. Involved in several processes, including negative regulation of collagen biosynthetic process; negative regulation of fibroblast migration; and negative regulation of hepatic stellate cell activation. Located in cytoplasm. Used to study liver cirrhosis and renal fibrosis. Biomarker of kidney disease and liver cirrhosis. Orthologous to human CYGB (cytoglobin). [provided by Alliance of Genome Resources, Apr 2022]

Cygb 基因产物(1)

mRNA Protein Name
NM_130744.2 NP_570100.1 cytoglobin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables catalase activity IDA
IDA: 通过直接分析推断
11320098 RGD
enables fatty acid peroxidase activity IDA
IDA: 通过直接分析推断
11320098 RGD
enables heme binding IDA
IDA: 通过直接分析推断
11320098 RGD
enables nitric oxide dioxygenase activity, heme protein as donor IDA
IDA: 通过直接分析推断
28393874 RGD
enables peroxidase activity IDA
IDA: 通过直接分析推断
11320098 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fatty acid oxidation IDA
IDA: 通过直接分析推断
11320098 RGD
involved in negative regulation of collagen biosynthetic process IDA
IDA: 通过直接分析推断
20719976 RGD
involved in negative regulation of fibroblast migration IDA
IDA: 通过直接分析推断
14647402 RGD
involved in negative regulation of hepatic stellate cell activation IDA
IDA: 通过直接分析推断
16581302 RGD
involved in nitric oxide catabolic process IMP
IMP: 通过突变表型推断
28393874 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
14660570 RGD
involved in response to oxidative stress IDA
IDA: 通过直接分析推断
11320098 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
14647402 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cytoglobin

HGb

globin f

histoglobin

stellate cell activation-associated protein

重组 Cygb 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72162 CYGB Protein, Rat (His-Myc) Q921A4 (M1-P190) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cygb NCBI NCBI:114757