1. Gene
  2. SGK3 - serum/glucocorticoid regulated kinase family, member 3 Gene

SGK3 - serum/glucocorticoid regulated kinase family, member 3 Gene

中文名称:血清/糖皮质激素调节激酶家族,成员 3

种属: Rattus norvegicus

同用名: Cisk; Sgkl

基因 ID: 171498 | 基因类型: protein coding

关于 SGK3

Primary_assembly 5: 9,346,040-9,415,476 reverse strand.mRatBN7.2:CM026978.1

This gene has 1 transcript (splice variant), 212 orthologues, 13 paralogues and is associated with 2 phenotypes. Biased expression in Spleen (RPKM 13.9), Thymus (RPKM 9.3) and 9 other tissues.

功能概要

预计该基因编码的蛋白可启动钾通道调节剂活性和蛋白丝氨酸/苏氨酸激酶活性。预计参与细胞内信号转导和肽基丝氨酸磷酸化。预计在没有配体的情况下作用于外在凋亡信号通路的负调节上游或负调节内。预测位于细胞质囊泡和核质中。与几个人类基因同源,包括 C8orf44-SGK3(C8orf44-SGK3 通读)。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable Potassium Channel regulator activity and protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Predicted to act upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in cytoplasmic vesicle and nucleoplasm. Orthologous to several human genes including C8orf44-SGK3 (C8orf44-SGK3 readthrough). [provided by Alliance of Genome Resources, Apr 2022]

SGK3 基因产物(1)

mRNA Protein Name
NM_001376043.1 NP_001362972.1 serine/threonine-protein kinase Sgk3

SGK3 蛋白结构

PX_CISK

PX_CISK: cd06870 (11 - 119)

STKc_SGK3

STKc_SGK3: cd05604 (164 - 489)

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  • 496 a.a.
蛋白主名 其他名称

serine/threonine-protein kinase Sgk3

cytokine-independent survival kinase

serum/glucocorticoid-regulated kinase 3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens SGK3 NCBI NCBI:23678