EPHB6 - EPH receptor B6 Gene

中文名称：EPH 受体 B6

种属: Homo sapiens

同用名: HEP

关于 EPHB6

功能概要

该基因编码跨膜蛋白家族的一个成员，该家族的功能是 ephrin-B 家族蛋白的受体。与该家族的其他成员不同，编码的蛋白质不包含功能性激酶结构域。这种蛋白质的活性可以影响细胞粘附和迁移。该基因的表达在肿瘤进展过程中下调，表明该蛋白可能抑制肿瘤侵袭和转移。可变剪接导致多个转录本变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]