2. Gene
  3. Cd27 - CD27 antigen Gene

Cd27 - CD27 antigen Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: S152; Tp55; Tnfrsf7

基因 ID: 21940 | 基因类型: protein coding

关于 Cd27

功能概要

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in negative regulation of apoptotic process and positive regulation of JNK cascade. Acts upstream of or within negative regulation of T cell apoptotic process. Located in external side of plasma membrane. Is expressed in several structures, including femur; hemolymphoid system; intestine; pituitary gland; and reproductive system. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 2. Orthologous to human CD27 (CD27 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd27 基因产物(3)

mRNA Protein Name
NM_001033126.2 NP_001028298.1 CD27 antigen isoform a precursor
NM_001042564.1 NP_001036029.1 CD27 antigen isoform b precursor
NM_001286753.1 NP_001273682.1 CD27 antigen isoform c precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9692890 MGI
enables transmembrane signaling receptor activity IDA
IDA: 通过直接分析推断
9366422 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in CD27 signaling pathway IDA
IDA: 通过直接分析推断
9366422 MGI
acts upstream of or within negative regulation of T cell apoptotic process IPI
IPI: 通过物理相互作用推断
9692890 MGI
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
9692890 MGI
involved in positive regulation of JNK cascade IDA
IDA: 通过直接分析推断
9692890 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
9833765 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
21508411 MGI
is active in plasma membrane IDA
IDA: 通过直接分析推断
9366422 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CD27 antigen

CD antigen 27

CD27L receptor

T-cell activation antigen CD27

tumor necrosis factor receptor superfamily member 7

重组 Cd27 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72743 CD27/TNFRSF7 Protein, Mouse (HEK293, His-Fc) P41272 (P24-R182) ≥95%
HY-P76216 CD27/TNFRSF7 Protein, Mouse (HEK293, His) P41272 (P24-R182) ≥95%
HY-P78256 CD27/TNFRSF7 Protein, Mouse (HEK293, mFc) P41272 (P24-R182) ≥95%

相关产品

Clinical Phase
抗体抑制剂 (3)
目录号 产品名 作用方式
纯度 Phase
HY-P99057 Varlilumab Inhibitor 96.09% Phase 2
HY-P990018 Boserolimab Inhibitor 99.00% Phase 2
HY-P99057A Varlilumab (anti-CD27) Inhibitor 99.68% Phase 2
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-113512 17-HDHA / 否
HY-120255 17(R)-HDHA / 否
HY-RS02216 CD27 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd27 NCBI NCBI:939
Canis familiaris Cd27 NCBI NCBI:611674
Macaca fascicularis Cd27 NCBI NCBI:102139476
Leporidae Cd27 NCBI
Rattus norvegicus Cd27 NCBI NCBI:500318
Macaca mulatta Cd27 NCBI NCBI:712693
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