2. Gene
  3. Tpo - thyroid peroxidase Gene

Tpo - thyroid peroxidase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 22018 | 基因类型: protein coding

关于 Tpo

功能概要

This gene encodes a membrane-bound glycoprotein. The encoded Enzyme plays a central role in thyroid gland function. The Enzyme functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid Hormones, thyroxine and triiodothyronine. Mice with homozygous missense mutations in this gene exhibit hypothyroid dwarfism and hearing impairment. [provided by RefSeq, Sep 2015]

Tpo 基因产物(1)

mRNA Protein Name
NM_009417.3 NP_033443.1 thyroid peroxidase precursor
蛋白主名 其他名称

thyroid peroxidase

重组 Tpo 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78045 TPO/Thyroid Peroxidase Protein, Mouse (HEK293, His) P35419 (G32-R834) ≥95%

相关产品

Approval
生物活性分子 (5)
目录号 产品名 作用方式
纯度 是否罕见病
HY-19883 Lusutrombopag Agonist 98.88% 否
HY-13463 Avatrombopag Agonist 99.83% 是
HY-W017113 2-Mercaptobenzothiazole Activator 99.85% 是
HY-13463B Avatrombopag hydrochloride Agonist 96.69% 是
HY-13463A Avatrombopag maleate Agonist 99.88% 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-145589 Rafutrombopag Agonist / Phase 1
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148748 Butyzamide Activator 99.62% 否
HY-112486 TA-316 98.04% 否
HY-W017894 TPO-L 99.40% 否
HY-100380 TPO agonist 1 Agonist ≥98.0% 否
HY-139915 MPO-IN-1 Inhibitor 99.02% 否
HY-15306S Eltrombopag-13C4 97.89% 否
HY-112486G TA-316 (GMP) Agonist / 否
HY-19883S Lusutrombopag-d13 Agonist 98.64% 否
HY-13463BS Avatrombopag-d8 hydrochloride Agonist / 否
HY-147691 MPO-IN-5 Inhibitor / 否
HY-153239 Eltrombopag methyl ester Agonist / 否
HY-RS14941 TPO Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tpo NCBI NCBI:7173
Macaca fascicularis Tpo NCBI NCBI:102125126
Rattus norvegicus Tpo NCBI NCBI:54314
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