2. Gene
  3. Tfrc - transferrin receptor Gene

Tfrc - transferrin receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TR; TFR; p90; CD71; TFR1; Trfr; Mtvr1; 2610028K12Rik; E430033M20Rik

基因 ID: 22042 | 基因类型: protein coding

关于 Tfrc

功能概要

This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor show impaired erythroid development and abnormal iron homeostasis. [provided by RefSeq, Sep 2015]

Tfrc 基因产物(2)

mRNA Protein Name
NM_001357298.1 NP_001344227.1 transferrin receptor protein 1
NM_011638.4 NP_035768.1 transferrin receptor protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16893896 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
10192390 MGI
involved in osteoclast differentiation IMP
IMP: 通过突变表型推断
19252502 MGI
involved in positive regulation of B cell proliferation IDA
IDA: 通过直接分析推断
26642240 MGI
involved in positive regulation of T cell proliferation IDA
IDA: 通过直接分析推断
26642240 MGI
involved in positive regulation of bone resorption IDA
IDA: 通过直接分析推断
19252502 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: 通过直接分析推断
26880306 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IEP
IEP: 通过表达模式推断
26880306 MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: 通过突变表型推断
26880306 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of HFE-transferrin receptor complex IDA
IDA: 通过直接分析推断
16893896 MGI
located in cell surface IDA
IDA: 通过直接分析推断
17716972 MGI
located in clathrin-coated pit IDA
IDA: 通过直接分析推断
18434600 MGI
located in early endosome IDA
IDA: 通过直接分析推断
26432893 MGI
located in endosome IDA
IDA: 通过直接分析推断
11092755 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
20424607 MGI
located in extracellular exosome IDA
IDA: 通过直接分析推断
19724054 MGI
located in membrane IMP
IMP: 通过突变表型推断
20080761 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
10444069 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
10444069 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
26880306 MGI
located in recycling endosome IDA
IDA: 通过直接分析推断
23395379 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transferrin receptor protein 1

mammary tumor virus receptor 1

重组 Tfrc 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72455 TFRC Protein, Mouse (HEK293, His) Q62351 (C89-F763) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14431 TFRC Human Pre-designed siRNA Set A Pre-designed Sets / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990780 Zeleciment / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tfrc NCBI NCBI:7037
Macaca fascicularis Tfrc NCBI NCBI:102136007
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