2. Gene
  3. SLC39A12 - solute carrier family 39 member 12 Gene

SLC39A12 - solute carrier family 39 member 12 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 39 成员 12

种属: Homo sapiens

同用名: ZIP12; ZIP-12; LZT-Hs8; bA570F3.1

基因 ID: 221074 | 基因类型: protein coding

关于 SLC39A12

Cytogenetic location: 10p12.33 Genomic coordinates (GRCh38): 10:17,951,918-18,043,285 (from NCBI)

This gene has 4 transcripts (splice variants), 189 orthologues and 6 paralogues. Restricted expression toward brain (RPKM 9.2).

功能概要

锌是数百种酶的必需辅助因子。它参与蛋白质、核酸、碳水化合物和脂质代谢，以及基因转录、生长、发育和分化的控制。 SLC39A12 属于显示锌转运蛋白结构特征的蛋白质亚家族 (Taylor 和 Nicholson，2003 [PubMed 12659941]) 。[OMIM 提供，2008 年 8 月]

Zinc is an essential cofactor for hundreds of Enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Aug 2008]

SLC39A12 基因产物(4)

mRNA Protein Name
NM_001145195.2 NP_001138667.1 zinc transporter ZIP12 isoform 1 precursor
NM_001282733.2 NP_001269662.1 zinc transporter ZIP12 isoform 3 precursor
NM_001282734.2 NP_001269663.1 zinc transporter ZIP12 isoform 4
NM_152725.4 NP_689938.2 zinc transporter ZIP12 isoform 2 precursor

SLC39A12 蛋白结构

Zip

Zip: ZIP Zinc transporter (369 - 683)

  • 0
  • 200
  • 400
  • 600
  • 691 a.a.
蛋白主名 其他名称

zinc transporter ZIP12

LIV-1 subfamily of ZIP zinc transporter 8

关联疾病

疾病名称 别名
Acrodermatitis Enteropathica, Zinc-Deficiency Type

Acrodermatitis Enteropathica

AEZ

Enteropathica

Brandt Syndrome

Ae

Acrodermatitis Enteropathica Zinc Deficiency Type

Danbolt-Cross Syndrome

Acrodermatitis Enteropathica, Zinc Deficiency Type

Inherited Zinc Deficiency

Acrodermatitis Enteropathica, Zinc Deficiency

Danbolt-Closs Syndrome

Primary Zinc Malabsorption Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13231 SLC39A12 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SLC39A12 MGD MGI:2139274
Felis catus SLC39A12 VGNC VGNC:65356
Canis familiaris SLC39A12 VGNC VGNC:46401
Rattus norvegicus SLC39A12 RGD RGD:1309305
Bos taurus SLC39A12 VGNC VGNC:34860
Macaca mulatta SLC39A12 VGNC VGNC:77539
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