2. Gene
  3. ADGRG5 - adhesion G protein-coupled receptor G5 Gene

ADGRG5 - adhesion G protein-coupled receptor G5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：粘附 G 蛋白偶联受体 G5

种属: Homo sapiens

同用名: PGR27; GPR114

基因 ID: 221188 | 基因类型: protein coding

关于 ADGRG5

Cytogenetic location: 16q21 Genomic coordinates (GRCh38): 16:57,529,073-57,577,189 (from NCBI)

This gene has 7 transcripts (splice variants), 113 orthologues and 42 paralogues. Biased expression in lymph node (RPKM 4.6), spleen (RPKM 3.3) and 13 other tissues.

功能概要

该基因编码 G 蛋白偶联受体粘附家族的成员。该家族成员的特点是长 N 末端和多个功能域。它们可能在免疫系统和中枢神经系统中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 1 月]

This gene encodes a member of the adhesion family of G-protein coupled receptors. Members of this family are characterized by long N-termini and multiple functional domains. They may play a role in the immune system as well as in the central nervous system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

ADGRG5 基因产物(3)

mRNA Protein Name
NM_001304376.3 NP_001291305.1 adhesion G-protein coupled receptor G5 isoform 1 precursor
NM_001318481.2 NP_001305410.1 adhesion G-protein coupled receptor G5 isoform 2 precursor
NM_153837.4 NP_722579.1 adhesion G-protein coupled receptor G5 isoform 1 precursor

ADGRG5 蛋白结构

GPS

GPS: GPCR proteolysis site, GPS, motif (186 - 233)

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (248 - 498)

  • 0
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  • 500
  • 528 a.a.
蛋白主名 其他名称

adhesion G-protein coupled receptor G5

G protein-coupled receptor 114

重组 ADGRG5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76960 GPR114 Protein, Human (HEK293, Fc) Q8IZF4 (E22-G184) ≥95%

关联疾病

疾病名称 别名
Polymicrogyria, Bilateral Frontoparietal

Bilateral Frontoparietal Polymicrogyria

BFPP

Cerebellar Ataxia With Neuronal Migration Defect
Usher Syndrome, Type Iic

Usher Syndrome Type 2c

USH2C

Usher Syndrome, Type 2c

Usher Syndrome, Type Iic, Gpr98/Pdzd7 Digenic

Usher Syndrome Type Iic

Usher Syndrome, Type 2c, Gpr98/Pdzd7 Digenic

Usher Syndrome 2c

Usher'S Syndrome Type 2c

Usher Syndrome Type Iic Gpr98/Pdzd7 Digenic
Alveoli Adenoma

Alveolar Adenoma

Adenoma Of Alveoli

Adenoma Of The Alveoli
Bronchial Benign Neoplasm

Bronchus Neoplasm

Neoplasm Of Bronchus

Bronchial Neoplasms

Bronchial Neoplasm
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101483 Dihydromunduletone Antagonist 99.96% 否
HY-RS00358 ADGRG5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ADGRG5 VGNC VGNC:25668
Rattus norvegicus ADGRG5 RGD RGD:1305559
Macaca mulatta ADGRG5 VGNC VGNC:69634
Felis catus ADGRG5 VGNC VGNC:59636
Mus musculus ADGRG5 MGD MGI:2685955
Canis familiaris ADGRG5 VGNC VGNC:37647
Others ADGRG5 NCBI
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