1. Gene
  2. NEGR1 - neuronal growth regulator 1 Gene

NEGR1 - neuronal growth regulator 1 Gene

中文名称:神经元生长调节因子 1

种属: Homo sapiens

同用名: Ntra; KILON; IGLON4; DMML2433

基因 ID: 257194 | 基因类型: protein coding

关于 NEGR1

Cytogenetic location: 1p31.1 Genomic coordinates (GRCh38): 1:71,395,943-72,282,539 (from NCBI)

This gene has 5 transcripts (splice variants), 213 orthologues and 5 paralogues. Broad expression in brain (RPKM 13.7), fat (RPKM 5.3) and 18 other tissues.

功能概要

预计在多个过程的上游或内部起作用,包括进食行为;运动行为;和神经元投射发育的正调节。预测位于胞外区和质膜。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to act upstream of or within several processes, including feeding behavior; locomotory behavior; and positive regulation of neuron projection development. Predicted to be located in extracellular region and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

NEGR1 基因产物(1)

mRNA Protein Name
NM_173808.3 NP_776169.2 neuronal growth regulator 1 precursor

NEGR1 蛋白结构

I-set

I-set: Immunoglobulin I-set domain (46 - 135)

I-set

I-set: Immunoglobulin I-set domain (139 - 209)

I-set

I-set: Immunoglobulin I-set domain (228 - 312)

  • 0
  • 100
  • 200
  • 300
  • 354 a.a.
蛋白主名 其他名称

neuronal growth regulator 1

IgLON family member 4

重组 NEGR1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76508 NEGR1 Protein, Human (HEK293, His) Q7Z3B1-1 (V38-G324) ≥95%

关联疾病

疾病名称 别名
Niemann-Pick Disease, Type C2

NPC2

Niemann-Pick Disease Type C2

Niemann-Pick C2 Disease

Niemann-Pick Disease C2

Niemann-Pick Disease

Sphingomyelin/Cholesterol Lipidosis

Niemann-Pick Diseases

Lipoid Histiocytosis

Sphingomyelin Lipidosis

Sphingomyelinase Deficiency Disease

Lipid Histiocytosis

Neuronal Cholesterol Lipidosis

Neuronal Lipidosis

Npd

Sphingomyelinase Deficiency

Niemann-Pick Disease, Type A

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus NEGR1 RGD RGD:708416
Bos taurus NEGR1 VGNC VGNC:106836
Mus musculus NEGR1 MGD MGI:2444846
Macaca mulatta NEGR1 VGNC VGNC:81481
Felis catus NEGR1 VGNC VGNC:107589
Canis familiaris NEGR1 VGNC VGNC:54049
Others NEGR1 NCBI