NEGR1 蛋白, Human (HEK293, His)

The NEGR1 protein is associated with cell adhesion, suggesting a role in important cellular interactions. Its potential function as a transneural growth-promoting factor in regenerating axonal sprouting suggests a dynamic role in promoting neuronal growth. NEGR1 Protein, Human (HEK293, His) is the recombinant human-derived NEGR1 protein, expressed by HEK293 , with C-His labeled tag. The total length of NEGR1 Protein, Human (HEK293, His) is 287 a.a., with molecular weight of 45-48 KDa.

NEGR1 蛋白似乎与细胞粘附有关，表明其在介导对细胞过程至关重要的相互作用中具有潜在作用。它作为哺乳动物大脑再生轴突萌芽中的跨神经生长促进因子的假定功能表明其在促进神经元生长中的动态作用。与其他生长促进因子的相似性表明 NEGR1 可能参与再生过程，特别是在大脑中轴突萌芽的情况下。阐明 NEGR1 参与细胞粘附并促进再生轴突萌芽的具体机制，可以为其在神经发育和再生中的作用提供有价值的见解。对 NEGR1 功能的进一步探索可能有助于更好地理解其对哺乳动物大脑内神经元可塑性和再生过程的潜在影响。

Measured by its ability to the proliferation of SH-SY5Y Human neuroblastoma cells. The ED₅₀ for this effect is 14.38μg/mL, corresponding to a specific activity is 69.541 Unit/mg.

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  Measured by its ability to the proliferation of SH-SY5Y Human neuroblastoma cells.The ED₅₀ for this effect is 14.38μg/mL, corresponding to a specific activity is 69.541 Unit/mg.

Human

HEK293

C-His

Q7Z3B1-1 (V38-G324)

257194  [NCBI]

VDFPWAAVDNMMVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTVNEGTNVTLTCLATGKPEPSISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVRKVKVVVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKKLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITG

Approximately 42-55 kDa due to the glycosylation

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.