2. Gene
  3. TAFA5 - TAFA chemokine like family member 5 Gene

TAFA5 - TAFA chemokine like family member 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：TAFA 趋化因子样家族成员 5

种属: Homo sapiens

同用名: TAFA-5; FAM19A5; UNQ5208; QLLK5208

基因 ID: 25817 | 基因类型: protein coding

关于 TAFA5

Cytogenetic location: 22q13.32 Genomic coordinates (GRCh38): 22:48,489,553-48,751,932 (from NCBI)

This gene has 5 transcripts (splice variants) and 233 orthologues. Biased expression in brain (RPKM 13.2), endometrium (RPKM 3.4) and 8 other tissues.

功能概要

该基因是 TAFA 家族的成员，该家族由五个高度同源的基因组成，编码小的分泌蛋白。这些蛋白质在固定位置包含保守的半胱氨酸残基，并且与 CC 趋化因子家族的成员 MIP-1alpha 有远缘关系。 TAFA 蛋白主要在大脑的特定区域表达，并被假定作为大脑特异性趋化因子或神经因子发挥作用，充当免疫和神经细胞的调节剂。[RefSeq 提供，2013 年 9 月]

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells. [provided by RefSeq, Sep 2013]

TAFA5 基因产物(2)

mRNA Protein Name
NM_001082967.3 NP_001076436.1 chemokine-like protein TAFA-5 isoform 1 precursor
NM_015381.7 NP_056196.2 chemokine-like protein TAFA-5 isoform 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor binding IPI
IPI: 通过物理相互作用推断
29453251 GOA
enables receptor ligand activity IPI
IPI: 通过物理相互作用推断
29453251 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
29453251 GOA
acts upstream of or within negative regulation of vascular associated smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
29453251 GOA
acts upstream of or within negative regulation of vascular associated smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
29453251 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
29453251 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TAFA5 蛋白结构

TAFA

TAFA: TAFA family (42 - 131)

  • 0
  • 100
  • 132 a.a.
蛋白主名 其他名称

chemokine-like protein TAFA-5

TAFA protein 5

重组 TAFA5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700984 TAFA5/FAM19A5 Protein, Human (His) NP_056196 (T37-S125) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14183 TAFA5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus TAFA5 VGNC VGNC:65941
Canis familiaris TAFA5 VGNC VGNC:108221
Bos taurus TAFA5 VGNC VGNC:28779
Rattus norvegicus TAFA5 RGD RGD:1562115
Mus musculus TAFA5 MGD MGI:2146182
Others TAFA5 NCBI
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