1. Gene
  2. REM1 - RRAD and GEM like GTPase 1 Gene

REM1 - RRAD and GEM like GTPase 1 Gene

中文名称:RRAD 和创业板样 GTPase 1

种属: Homo sapiens

同用名: GES; GD:REM

基因 ID: 28954 | 基因类型: protein coding

关于 REM1

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:31,475,288-31,484,895 (from NCBI)

This gene has 1 transcript (splice variant), 169 orthologues and 35 paralogues. Broad expression in fat (RPKM 3.0), endometrium (RPKM 2.6) and 21 other tissues.

功能概要

该基因编码的蛋白质是一种 GTP 酶,是 Ras 样 GTP 结合蛋白家族的成员。编码的蛋白质在内皮细胞中表达,在那里它促进肌动蛋白细胞骨架的重组和细胞的形态学变化。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin Cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008]

REM1 基因产物(1)

mRNA Protein Name
NM_014012.6 NP_054731.2 GTP-binding protein REM 1

REM1 蛋白结构

Ras

Ras: Ras family (82 - 243)

  • 0
  • 100
  • 200
  • 298 a.a.
蛋白主名 其他名称

GTP-binding protein REM 1

GTPase-regulating endothelial cell sprouting

关联疾病

疾病名称 别名
Mobitz Type Ii Atrioventricular Block

Mobitz Ii Atrioventricular Block

Mobitz Ii Atrioventricular Block

Immunodeficiency 18

IMD18

Cd3-Epsilon Deficiency

Immunodeficiency 18, Scid Variant

Cd3epsilon Deficiency

Immunodeficiency 18, Severe Combined Immunodeficiency Variant

Immunodeficiency, Type 18

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus REM1 VGNC VGNC:33863
Macaca mulatta REM1 VGNC VGNC:108026
Mus musculus REM1 MGD MGI:1097696
Canis familiaris REM1 VGNC VGNC:45472
Rattus norvegicus REM1 RGD RGD:1306560
Felis catus REM1 VGNC VGNC:64569
Others REM1 NCBI