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  2. Lpar4 - lysophosphatidic acid receptor 4 Gene

Lpar4 - lysophosphatidic acid receptor 4 Gene

中文名称:溶血磷脂酸受体 4

种属: Rattus norvegicus

同用名: Gpr23; RGD1563686

基因 ID: 302378 | 基因类型: protein coding

关于 Lpar4

Primary_assembly X: 72,033,486-72,046,977 forward strand.mRatBN7.2:CM026994.1

This gene has 1 transcript (splice variant), 174 orthologues, 14 paralogues and is associated with 2 phenotypes. Biased expression in Muscle (RPKM 24.), Heart (RPKM 21.5) and 9 other tissues.

功能概要

预测该基因编码的蛋白具有溶血磷脂酸结合活性和溶血磷脂酸受体活性。预计参与磷脂酶 C 激活 G 蛋白偶联信号通路中 Rho 蛋白信号转导的正向调节和胞质钙离子浓度的正向调节。预测位于核体和质膜。预计是质膜的组成部分。与人类 LPAR4(溶血磷脂酸受体 4)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable lysophosphatidic acid binding activity and lysophosphatidic acid receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Predicted to be located in nuclear body and plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human LPAR4 (lysophosphatidic acid receptor 4). [provided by Alliance of Genome Resources, Apr 2022]

Lpar4 基因产物(1)

mRNA Protein Name
NM_001106940.1 NP_001100410.1 lysophosphatidic acid receptor 4

Lpar4 蛋白结构

7tmA_LPAR4

7tmA_LPAR4: cd15155 (39 - 66)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (39 - 321)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (73 - 98)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (110 - 140)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (152 - 174)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (200 - 229)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (241 - 271)

7tmA_LPAR4

7tmA_LPAR4: cd15155 (289 - 314)

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  • 370 a.a.
蛋白主名 其他名称

lysophosphatidic acid receptor 4

G protein-coupled receptor 23

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lpar4 NCBI NCBI:2846