Ptgdr2 - prostaglandin D2 receptor 2 Gene

中文名称：前列腺素 D2 受体 2

种属: Rattus norvegicus

同用名: Gpr44

关于 Ptgdr2

功能概要

预测该基因编码的蛋白编码的蛋白可启动神经肽结合活性和前列腺素受体活性。预计参与钙介导的信号传导；趋化性;和神经肽信号通路。预测作用于腺苷酸环化酶抑制 G 蛋白偶联受体信号通路的上游或内部；雄性生殖细胞增殖的负调节； G 蛋白偶联受体信号通路的正调控。预计在神经元投射中活跃。预计是质膜的组成部分。该基因的人类直系同源物与哮喘有关。与人类 PTGDR2（前列腺素 D2 受体 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable neuropeptide binding activity and Prostaglandin Receptor activity. Predicted to be involved in calcium-mediated signaling; chemotaxis; and neuropeptide signaling pathway. Predicted to act upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; negative regulation of male germ cell proliferation; and positive regulation of G protein-coupled receptor signaling pathway. Predicted to be active in neuron projection. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human PTGDR2 (prostaglandin D2 receptor 2). [provided by Alliance of Genome Resources, Apr 2022]