Ms4a1 - membrane spanning 4-domains A1 Gene

中文名称：跨膜 4 域 A1

种属: Rattus norvegicus

关于 Ms4a1

功能概要

该基因编码的蛋白可启动表皮生长因子受体结合活性。预计参与多个过程，包括B细胞受体信号通路；钙离子运输；和蛋白质四聚化。预计在对细菌的反应上游或反应内起作用。预计位于质膜外侧；核质；和质膜筏。肾小球肾炎的生物标志物。该基因的人类直系同源物与常见的可变免疫缺陷有关。与人类 MS4A1 同源（膜跨越 4 个结构域 A1）。 [由基因组资源联盟提供，2022 年 4 月]

Enables epidermal growth factor receptor binding activity. Predicted to be involved in several processes, including B cell receptor signaling pathway; calcium ion transport; and protein tetramerization. Predicted to act upstream of or within response to bacterium. Predicted to be located in external side of plasma membrane; nucleoplasm; and plasma membrane raft. Biomarker of glomerulonephritis. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human MS4A1 (membrane spanning 4-domains A1). [provided by Alliance of Genome Resources, Apr 2022]