1. Gene
  2. Il1rapl1 - interleukin 1 receptor accessory protein-like 1 Gene

Il1rapl1 - interleukin 1 receptor accessory protein-like 1 Gene

种属: Mus musculus

同用名: IL1R8; MRX34; OPHN4; IL1RAPL; TIGIRR-2; IL1RAPL-1; C030039N24; 6330532G10Rik

基因 ID: 331461 | 基因类型: protein coding

关于 Il1rapl1

功能概要

Enables signaling receptor binding activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; nervous system development; and positive regulation of nervous system development. Located in cell surface and dendrite. Is expressed in central nervous system; dorsal root ganglion; eye; lung; and trigeminal nerve. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability 21. Orthologous to human IL1RAPL1 (interleukin 1 receptor accessory protein like 1). [provided by Alliance of Genome Resources, Apr 2022]

Il1rapl1 基因产物(1)

mRNA Protein Name
NM_001160403.2 NP_001153875.1 interleukin-1 receptor accessory protein-like 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21940441 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
21940441 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
21940441 MGI
involved in neuron differentiation IDA
IDA: 通过直接分析推断
21940441 MGI
involved in positive regulation of dendrite morphogenesis IMP
IMP: 通过突变表型推断
21940441 MGI
involved in positive regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
21940441 MGI
involved in positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
25908590 MGI
involved in presynaptic membrane assembly IMP
IMP: 通过突变表型推断
21940441 MGI
involved in synaptic membrane adhesion IDA
IDA: 通过直接分析推断
21940441 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
21940441 MGI
located in dendrite IDA
IDA: 通过直接分析推断
21940441 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

interleukin-1 receptor accessory protein-like 1

X-linked interleukin-1 receptor accessory protein-like 1

重组 Il1rapl1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76998 IL1RAPL1 Protein, Mouse (HEK293, Fc) P59823 (R25-T357) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Il1rapl1 NCBI NCBI:11141