2. Gene
  3. Postn - periostin, osteoblast specific factor Gene

Postn - periostin, osteoblast specific factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PN; PLF; Osf2; OSF-2; A630052E07Rik

基因 ID: 50706 | 基因类型: protein coding

关于 Postn

功能概要

This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in Cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Postn 基因产物(6)

mRNA Protein Name
NM_001198765.1 NP_001185694.1 periostin isoform 2 precursor
NM_001198766.1 NP_001185695.1 periostin isoform 3 precursor
NM_001313898.1 NP_001300827.1 periostin isoform 4 precursor
NM_001313899.1 NP_001300828.1 periostin isoform 5 precursor
NM_001368678.1 NP_001355607.1 periostin isoform 6 precursor
NM_015784.3 NP_056599.1 periostin isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables heparin binding IDA
IDA: 通过直接分析推断
7663166 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell adhesion IDA
IDA: 通过直接分析推断
10404027 MGI
involved in cellular response to vitamin K IDA
IDA: 通过直接分析推断
18450759 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: 通过突变表型推断
16314533 MGI
acts upstream of or within regulation of Notch signaling pathway IMP
IMP: 通过突变表型推断
19723774 MGI
acts upstream of or within tissue development IMP
IMP: 通过突变表型推断
16314533 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
18450759 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
10404027 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

periostin

osteoblast specific factor 2 (fasciclin I-like)

osteoblast-specific factor 2

periostin-like factor

重组 Postn 蛋白

目录号 产品名 蛋白编号 纯度
HY-P73373 Periostin Protein, Mouse (HEK293, His) Q62009-1 (N24-Q811) ≥95%
HY-P78332 Periostin Protein, Mouse (Q62009-2, HEK293, His) Q62009-2/NP_056599.1 (N24-Q811) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10884 POSTN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Postn NCBI NCBI:10631
Rattus norvegicus Postn NCBI NCBI:361945
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