2. Gene
  3. Cxcr1 - C-X-C motif chemokine receptor 1 Gene

Cxcr1 - C-X-C motif chemokine receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：CXC 基序趋化因子受体 1

种属: Rattus norvegicus

同用名: Il8ra; IL-8R A

基因 ID: 54258 | 基因类型: protein coding

关于 Cxcr1

Primary_assembly 9: 75,766,770-75,771,084 reverse strand.mRatBN7.2:CM026982.1

This gene has 1 transcript (splice variant), 232 orthologues, 24 paralogues and is associated with 11 phenotypes. Restricted expression toward (RPKM 25.9).

功能概要

预测该基因编码的蛋白可启动趋化因子结合活性和趋化因子受体活性。预计参与多个过程，包括中性粒细胞趋化性；细胞溶质钙离子浓度的正向调节；和受体内化。预计是膜的组成部分。预计在质膜外侧活跃。膜增生性肾小球肾炎的生物标志物。该基因的人类直系同源物与人类免疫缺陷病毒传染病有关；肾盂肾炎;和尿路感染。与人类 CXCR1（CXC 基序趋化因子受体 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable chemokine binding activity and Chemokine Receptor activity. Predicted to be involved in several processes, including neutrophil chemotaxis; positive regulation of cytosolic calcium ion concentration; and receptor internalization. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Biomarker of membranoproliferative glomerulonephritis. Human ortholog(s) of this gene implicated in human immunodeficiency virus infectious disease; pyelonephritis; and urinary tract Infection. Orthologous to human CXCR1 (C-X-C motif Chemokine Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Cxcr1 基因产物(1)

mRNA Protein Name
NM_019310.2 NP_062183.1 C-X-C chemokine receptor type 1

Cxcr1 蛋白结构

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (44 - 320)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (44 - 71)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (78 - 103)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (114 - 144)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (155 - 177)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (203 - 231)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (239 - 269)

7tmA_CXCR1_2

7tmA_CXCR1_2: cd15178 (288 - 313)

  • 0
  • 100
  • 200
  • 300
  • 349 a.a.
蛋白主名 其他名称

C-X-C chemokine receptor type 1

chemokine (C-X-C motif) receptor 1

high affinity interleukin-8 receptor A

interleukin 8 receptor, alpha

相关产品

Clinical Phase
生物活性分子 (5)
目录号 产品名 作用方式
纯度 Phase
HY-15251 Reparixin Inhibitor 99.95% Phase 3
HY-15252 Reparixin L-lysine salt Inhibitor 99.66% Phase 3
HY-19519A Ladarixin sodium Antagonist 99.84% Phase 3
HY-10198 Navarixin Antagonist 98.90% Phase 2
HY-119339 SX-682 Inhibitor 99.67% Phase 2
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120878 CXCR2-IN-2 Antagonist 99.52% 否
HY-12927 SX-517 Antagonist 99.88% 否
HY-10011 SCH 563705 Antagonist 99.86% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cxcr1 NCBI NCBI:3577
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z