2. Gene
  3. DEPDC1B - DEP domain containing 1B Gene

DEPDC1B - DEP domain containing 1B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 DEP 域 1B

种属: Homo sapiens

同用名: XTP1; BRCC3

基因 ID: 55789 | 基因类型: protein coding

关于 DEPDC1B

Cytogenetic location: 5q12.1 Genomic coordinates (GRCh38): 5:60,596,912-60,700,166 (from NCBI)

This gene has 6 transcripts (splice variants), 201 orthologues and 3 paralogues. Broad expression in gall bladder (RPKM 6.2), testis (RPKM 3.3) and 14 other tissues.

功能概要

预测启用 GTPase 激活剂活动。参与细胞迁移和 Wnt 信号通路的正调控。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GTPase activator activity. Involved in cell migration and positive regulation of Wnt signaling pathway. [provided by Alliance of Genome Resources, Apr 2022]

DEPDC1B 基因产物(2)

mRNA Protein Name
NM_001145208.2 NP_001138680.1 DEP domain-containing protein 1B isoform 2
NM_018369.3 NP_060839.2 DEP domain-containing protein 1B isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell migration IMP
IMP: 通过突变表型推断
24971537 GOA
involved in positive regulation of Wnt signaling pathway IMP
IMP: 通过突变表型推断
24971537 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

DEPDC1B 蛋白结构

DEP

DEP: Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) (28 - 106)

RhoGAP

RhoGAP: RhoGAP domain (270 - 342)

  • 0
  • 100
  • 200
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  • 400
  • 500
  • 529 a.a.
蛋白主名 其他名称

DEP domain-containing protein 1B

HBV X-transactivated gene 8 protein

关联疾病

疾病名称 别名
Lung Cancer

Lung Carcinoma

Non-Small Cell Lung Carcinoma

Lung Cancer, Susceptibility To

Lung Cancer, Protection Against

Adenocarcinoma Of Lung, Somatic

Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer

Lung Neoplasm

Carcinoma Of Lung

Lung Non-Small Cell Carcinoma

Non-Small Cell Lung Cancer

Nsclc

Lung Neoplasms

Malignant Neoplasm Of Lung

Alveolar Cell Carcinoma

Nonsmall Cell Lung Cancer, Somatic

Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

Nonsmall Cell Lung Cancer, Susceptibility To

Lung Cancer, Somatic

Lung Cancer, Resistance To

Cancer Of Lung

Cancer Of Bronchus

Cancer Of The Lung

Lung Malignancies

Lung Malignant Tumors

Malignant Lung Tumor

Malignant Tumor Of Lung

Pulmonary Cancer

Pulmonary Carcinoma

Pulmonary Neoplasms

Respiratory Carcinoma

LNCR

Adenocarcinoma Of Lung

Neoplasm Of Lung

Cancer Lung

Carcinoma Non-Small Cell Lung

Carcinoma, Non-Small-Cell Lung

Lung Cancers

Lung Carcinomas

Cancer, Lung

Cancer, Lung, Non-Small Cell

Primary Malignant Neoplasm Of Lung

Bronchioloalveolar Adenocarcinoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03694 DEPDC1B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta DEPDC1B VGNC VGNC:71705
Mus musculus DEPDC1B MGD MGI:2145425
Felis catus DEPDC1B VGNC VGNC:61444
Rattus norvegicus DEPDC1B RGD RGD:1305799
Bos taurus DEPDC1B VGNC VGNC:28005
Canis familiaris DEPDC1B VGNC VGNC:39897
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