2. Gene
  3. SLC46A2 - solute carrier family 46 member 2 Gene

SLC46A2 - solute carrier family 46 member 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 46 成员 2

种属: Homo sapiens

同用名: Ly110; TSCOT

基因 ID: 57864 | 基因类型: protein coding

关于 SLC46A2

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:112,878,920-112,890,876 (from NCBI)

This gene has 2 transcripts (splice variants), 227 orthologues and 2 paralogues. Biased expression in lung (RPKM 9.2), skin (RPKM 5.1) and 6 other tissues.

功能概要

预测启用跨膜转运蛋白活动。参与包含 1 个信号通路的核苷酸结合活性寡聚结构域的正调控。预计位于细胞表面和质膜。预计是膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable transmembrane transporter activity. Involved in positive regulation of nucleotide-binding activity oligomerization domain containing 1 signaling pathway. Predicted to be located in cell surface and plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC46A2 基因产物(1)

mRNA Protein Name
NM_033051.4 NP_149040.3 thymic stromal cotransporter homolog
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cyclic-GMP-AMP transmembrane transporter activity IDA
IDA: 通过直接分析推断
34235268 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cyclic-GMP-AMP transmembrane import across plasma membrane IDA
IDA: 通过直接分析推断
34235268 GOA
involved in positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway IMP
IMP: 通过突变表型推断
28539433 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
34235268 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC46A2 蛋白结构

MFS_1

MFS_1: Major Facilitator Superfamily (85 - 420)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 475 a.a.
蛋白主名 其他名称

thymic stromal cotransporter homolog

thymic stromal co-transporter

关联疾病

疾病名称 别名
Folate Malabsorption, Hereditary

Hereditary Folate Malabsorption

Congenital Defect Of Folate Absorption

Congenital Folate Malabsorption

Folic Acid Transport Defect

HFM
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13261 SLC46A2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SLC46A2 MGD MGI:1353616
Felis catus SLC46A2 VGNC VGNC:65380
Rattus norvegicus SLC46A2 RGD RGD:1310485
Macaca mulatta SLC46A2 VGNC VGNC:77714
Canis familiaris SLC46A2 VGNC VGNC:46427
Bos taurus SLC46A2 VGNC VGNC:34885
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