2. Gene
  3. PTPRZ1 - protein tyrosine phosphatase receptor type Z1 Gene

PTPRZ1 - protein tyrosine phosphatase receptor type Z1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白酪氨酸磷酸酶受体 Z1 型

种属: Homo sapiens

同用名: PTPZ; HPTPZ; PTP18; PTPRZ; RPTPB; HPTPzeta; PTP-ZETA; RPTPbeta; phosphacan; R-PTP-zeta-2

基因 ID: 5803 | 基因类型: protein coding

关于 PTPRZ1

Cytogenetic location: 7q31.32 Genomic coordinates (GRCh38): 7:121,873,161-122,062,036 (from NCBI)

This gene has 21 transcripts (splice variants), 290 orthologues and 35 paralogues. Biased expression in brain (RPKM 103.2) and skin (RPKM 10.8).

功能概要

该基因编码受体蛋白酪氨酸磷酸酶家族的一个成员。该基因的表达仅限于中枢神经系统 (CNS) ，它可能参与中枢神经系统特定发育过程的调控。已经针对该基因描述了编码不同亚型的选择性剪接转录物变体。[RefSeq 提供，2011 年 5 月]

This gene encodes a member of the receptor protein tyrosine Phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

PTPRZ1 基因产物(5)

mRNA Protein Name
NM_001206838.2 NP_001193767.1 receptor-type tyrosine-protein phosphatase zeta isoform 2 precursor
NM_001206839.2 NP_001193768.1 receptor-type tyrosine-protein phosphatase zeta isoform 3 precursor
NM_001369395.1 NP_001356324.1 receptor-type tyrosine-protein phosphatase zeta isoform 4 precursor
NM_001369396.1 NP_001356325.1 receptor-type tyrosine-protein phosphatase zeta isoform 5
NM_002851.3 NP_002842.2 receptor-type tyrosine-protein phosphatase zeta isoform 1 precursor

PTPRZ1 蛋白结构

Carb_anhydrase

Carb_anhydrase: Eukaryotic-type carbonic anhydrase (38 - 299)

fn3

fn3: Fibronectin type III domain (313 - 401)

Y_phosphatase

Y_phosphatase: Protein-tyrosine phosphatase (1750 - 1990)

Y_phosphatase

Y_phosphatase: Protein-tyrosine phosphatase (2048 - 2280)

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  • 2000
  • 2315 a.a.
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase zeta

protein tyrosine phosphatase, receptor-type, Z polypeptide 1

重组 PTPRZ1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71777 PTPRZ1 Protein, Human (P.pastoris, His) P23471-1 (I36-Y300) ≥95%

关联疾病

疾病名称 别名
Generalized Epilepsy With Febrile Seizures Plus, Type 1

GEFSP1

GEFS+1

Generalized Epilepsy With Febrile Seizures Plus 1

Gefs+, Type 1

Generalised Epilepsy With Febrile Seizures Plus 1

Generalised Epilepsy With Febrile Seizures Plus Type 1

Generalized Epilepsy With Febrile Seizures Plus Type 1

Gefs+ Type 1

Epilepsy, Generalized, With Febrile Seizures Plus, Type 1
Oligodendroglioma

Oligodendroglial Neoplasm

Oligodendroglial Tumor

Oligodendroglial Tumors

Well Differentiated Oligodendroglioma
Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma
Generalized Epilepsy With Febrile Seizures Plus

Gefs+

Genetic Epilepsy With Febrile Seizures Plus

Generalized Epilepsy With Febrile Seizures-Plus

Genetic Epilepsy With Febrile Seizures-Plus

Epilepsy, Generalized, With Febrile Seizures Plus
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103693 NAZ2329 Inhibitor 99.02% 否
HY-RS11452 PTPRZ1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PTPRZ1 VGNC VGNC:76625
Canis familiaris PTPRZ1 VGNC VGNC:54793
Bos taurus PTPRZ1 VGNC VGNC:33560
Felis catus PTPRZ1 VGNC VGNC:69184
Mus musculus PTPRZ1 MGD MGI:97816
Rattus norvegicus PTPRZ1 RGD RGD:3455
Others PTPRZ1 NCBI
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