RPS4Y1 - ribosomal protein S4 Y-linked 1 Gene

中文名称：核糖体蛋白 S4 Y-linked 1

种属: Homo sapiens

同用名: S4; RPS4Y

关于 RPS4Y1

功能概要

细胞质核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码核糖体蛋白 S4，它是 40S 亚基的一个组成部分。核糖体蛋白 S4 是唯一已知由一个以上基因编码的核糖体蛋白，即该基因和核糖体蛋白 S4，X 连锁 (RPS4X) 。由这些基因编码的 2 种亚型并不相同，但在功能上是等同的。核糖体蛋白 S4 属于核糖体蛋白 S4E 家族。有人提出，核糖体蛋白 S4 基因的单倍体不足在特纳综合征中起作用；然而，这个假设是有争议的。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供，2008 年 7 月]

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]