2. Gene
  3. ACOD1 - aconitate decarboxylase 1 Gene

ACOD1 - aconitate decarboxylase 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：乌头酸脱羧酶 1

种属: Homo sapiens

同用名: CAD; IRG1

基因 ID: 730249 | 基因类型: protein coding

关于 ACOD1

Cytogenetic location: 13q22.3 Genomic coordinates (GRCh38): 13:76,948,511-76,958,638 (from NCBI)

This gene has 2 transcripts (splice variants) and 188 orthologues. Low expression observed in reference dataset.

功能概要

启用乌头酸脱羧酶活性。参与防御反应；抗菌体液反应的正调节；和对脂多糖的耐受性诱导。预测在线粒体中活跃。 [由基因组资源联盟提供，2022 年 4 月]

Enables aconitate decarboxylase activity. Involved in defense response; positive regulation of antimicrobial humoral response; and tolerance induction to lipopolysaccharide. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

ACOD1 基因产物(1)

mRNA Protein Name
NM_001258406.2 NP_001245335.1 cis-aconitate decarboxylase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aconitate decarboxylase activity IDA
IDA: 通过直接分析推断
23610393 GOA
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
31548418 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
23609450 GOA
involved in defense response IDA
IDA: 通过直接分析推断
23610393 GOA
involved in positive regulation of antimicrobial humoral response IDA
IDA: 通过直接分析推断
23610393 GOA
involved in tolerance induction to lipopolysaccharide IDA
IDA: 通过直接分析推断
23609450 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACOD1 蛋白结构

MmgE_PrpD

MmgE_PrpD: MmgE/PrpD family (5 - 447)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 481 a.a.
蛋白主名 其他名称

cis-aconitate decarboxylase

cis-aconitic acid decarboxylase

关联疾病

疾病名称 别名
Alzheimer Disease 5

Ad5

Alzheimer'S Disease 5

Alzheimer Disease, Familial, 5

Alzheimer Disease-5

Alzheimer Disease, Familial 5

Alzheimer'S Disease 5, Late Onset

Alzheimer Disease, Familial, Type 5
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16239 Acod1 Mouse Pre-designed siRNA Set A / 否
HY-RS00172 ACOD1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ACOD1 VGNC VGNC:37515
Felis catus ACOD1 VGNC VGNC:59517
Mus musculus ACOD1 MGD MGI:103206
Rattus norvegicus ACOD1 RGD RGD:1563454
Macaca mulatta ACOD1 VGNC VGNC:106248
Bos taurus ACOD1 VGNC VGNC:58358
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