2. Gene
  3. YWHAB - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta Gene

YWHAB - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：酪氨酸 3-单加氧酶/色氨酸 5-单加氧酶激活蛋白 β

种属: Homo sapiens

同用名: HS1; GW128; YWHAA; KCIP-1; HEL-S-1

基因 ID: 7529 | 基因类型: protein coding

关于 YWHAB

Cytogenetic location: 20q13.12 Genomic coordinates (GRCh38): 20:44,885,705-44,908,532 (from NCBI)

This gene has 8 transcripts (splice variants), 269 orthologues and 6 paralogues. Ubiquitous expression in brain (RPKM 158.2), lymph node (RPKM 85.8) and 24 other tissues.

功能概要

该基因编码属于 14-3-3 蛋白家族的一种蛋白，该蛋白的成员通过与含磷酸丝氨酸的蛋白结合来介导信号转导。这种高度保守的蛋白质家族存在于植物和哺乳动物中。编码的蛋白质已被证明与 RAF1 和 CDC25 磷酸酶相互作用，表明它可能在连接促有丝分裂信号和细胞周期机制方面发挥作用。已经为该基因鉴定了编码相同蛋白质的两个转录物变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both Plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

YWHAB 基因产物(2)

mRNA Protein Name
NM_003404.5 NP_003395.1 2014/3/3 protein beta/alpha
NM_139323.4 NP_647539.1 2014/3/3 protein beta/alpha

YWHAB 蛋白结构

14-3-3

14-3-3: 14-3-3 protein (6 - 237)

  • 0
  • 100
  • 200
  • 246 a.a.
蛋白主名 其他名称

14-3-3 protein beta/alpha

14-3-3 alpha

重组 YWHAB 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74439 14-3-3 beta Protein, Human (GST) P31946 (M1-N246) ≥95%
HY-P74440 14-3-3 beta Protein, Human P31946 (M1-N246) ≥95%
HY-P700304 14-3-3 beta Protein, Human (His) P31946 (M1-N246) ≥95%

关联疾病

疾病名称 别名
Chlamydia

Chlamydial Infection

Chlamydia Trachomatis Infectious Disease

Chlamydial Disease

Chlamydia Infections
Eosinophilic Meningitis

Eosinophilic Meningoencephalitis Due To Angiostrongylus Cantonensis
Hyperinsulinemic Hypoglycemia, Familial, 5

Hyperinsulinism Due To Insr Deficiency

HHF5

Familial Hyperinsulinemic Hypoglycemia 5

Hyperinsulinemic Hypoglycemia Due To Insr Deficiency

Hyperinsulinemic Hypoglycemia Due To Insulin Receptor Deficiency

Congenital Hyperinsulinism

Persistent Hyperinsulinemic Hypoglycemia Of Infancy

Phhi

Hyperinsulinemic Hypoglycemia Familial 5
Chronic Meningitis
Lymphogranuloma Venereum

Climatic Or Tropical Bubo

Durand-Nicolas-Favre Disease

Lymphogranuloma Inguinale

Poradenitis Inguinale

Strumous Bubo

Lgv
Granuloma Inguinale

Donovanosis

Pudendal Ulcer

Granuloma Inguinale Tropicum

Granuloma Pudendi Tropicum
Chromosome 17p13.3, Centromeric, Duplication Syndrome

Chromosome 17p13.3 Duplication Syndrome

17p13.3 Duplication Syndrome

17p13.3 Microduplication Syndrome

Trisomy 17p13.3

Chromosome 17p13.3 Centromeric Duplication Syndrome

Dup(17)(P13.3)
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15940 YWHAB Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris YWHAB VGNC VGNC:48508
Rattus norvegicus YWHAB RGD RGD:61998
Mus musculus YWHAB MGD MGI:1891917
Felis catus YWHAB VGNC VGNC:67154
Macaca mulatta YWHAB VGNC VGNC:78819
Bos taurus YWHAB VGNC VGNC:37044
Macaca fascicularis YWHAB NCBI NCBI:101926442
Others YWHAB NCBI
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