1. Gene
  2. USP9Y - ubiquitin specific peptidase 9 Y-linked Gene

USP9Y - ubiquitin specific peptidase 9 Y-linked Gene

中文名称:泛素特异性肽酶 9 Y 连接

种属: Homo sapiens

同用名: DFFRY; SPGFY2

基因 ID: 8287 | 基因类型: protein coding

关于 USP9Y

Cytogenetic location: Yq11.221 Genomic coordinates (GRCh38): Y:12,701,231-12,860,839 (from NCBI)

功能概要

该基因是肽酶 C19 家族的成员。它编码一种类似于泛素特异性蛋白酶的蛋白质,后者从泛素融合前体和泛素化蛋白质中切割泛素部分。[RefSeq 提供,2009 年 3 月]

This gene is a member of the peptidase C19 family. It encodes a protein that is similar to ubiquitin-specific proteases, which cleave the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. [provided by RefSeq, Mar 2009]

USP9Y 基因产物(1)

mRNA Protein Name
NM_004654.4 NP_004645.2 probable ubiquitin carboxyl-terminal hydrolase FAF-Y
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cysteine-type deubiquitinase activity IDA
IDA: 通过直接分析推断
12895410 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

USP9Y 蛋白结构

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (1559 - 1955)

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  • 2555 a.a.
蛋白主名 其他名称

probable ubiquitin carboxyl-terminal hydrolase FAF-Y

azoospermia factor A

关联疾病

疾病名称 别名
Spermatogenic Failure, Y-Linked, 2

SPGFY2

Spermatogenic Failure, Nonobstructive, Y-Linked

Y-Linked Spermatogenic Failure 2

Azoospermia, Nonobstructive, Y-Linked

Oligozoospermia, Nonobstructive, Y-Linked

Oligospermia, Nonobstructive, Y-Linked

Spermatogenic Arrest, Y-Linked

Nonobstructive Y-Linked Spermatogenic Failure

Spermatogenic Failure Y-Linked 2

Azoospermia Non-Obstructive Y-Linked

Non-Obstructive Azoospermia And Infertility

Oligospermia Non-Obstructive Y-Linked

Oligozoospermia Non-Obstructive Y-Linked

Spermatogenic Arrest Y-Linked

Spermatogenic Failure Nonobstructive Y-Linked

Partial Deletion Of Y

Partial Chromosome Y Deletion

Partial Deletion Of Y Chromosome Short Arm

Partial Deletion Of Chromosome Y

Partial Deletion Of The Long Arm Of The Y Chromosome

Y-Chromosome Microdeletions

Male Sterility Due To Chromosome Y Deletion

Y Chromosome Deletions

Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility

Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism

Infertility
Phelan-Mcdermid Syndrome

Chromosome 22q13.3 Deletion Syndrome

22q13.3 Deletion Syndrome

Telomeric 22q13 Monosomy Syndrome

PHMDS

Deletion 22q13 Syndrome

22q13.3 Deletion

Deletion 22q13.3 Syndrome

Monosomy 22q13

Monosomy 22q13.3

22q13 Deletion Syndrome

Monosomy 22q13 Syndrome

22q13 Deletion

Chromosome Deletion

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus USP9Y MGD MGI:1313274
Rattus norvegicus USP9Y RGD RGD:9087771