2. Gene
  3. ACSS1 - acyl-CoA synthetase short chain family member 1 Gene

ACSS1 - acyl-CoA synthetase short chain family member 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：酰基辅酶 A 合成酶短链家族成员 1

种属: Homo sapiens

同用名: ACAS2L; ACECS1; AceCS2L

基因 ID: 84532 | 基因类型: protein coding

关于 ACSS1

Cytogenetic location: 20p11.21 Genomic coordinates (GRCh38): 20:25,006,237-25,058,139 (from NCBI)

This gene has 5 transcripts (splice variants), 188 orthologues and 13 paralogues. Broad expression in placenta (RPKM 70.4), duodenum (RPKM 23.0) and 24 other tissues.

功能概要

该基因编码线粒体乙酰辅酶 A 合成酶。小鼠体内的一种类似蛋白质通过催化乙酸转化为乙酰辅酶 A，在三羧酸循环中发挥重要作用。已经观察到该基因编码多种亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 11 月]

This gene encodes a mitochondrial acetyl-CoA synthetase Enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

ACSS1 基因产物(4)

mRNA Protein Name
NM_001252675.2 NP_001239604.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 2 precursor
NM_001252676.2 NP_001239605.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 3
NM_001252677.2 NP_001239606.1 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 4 precursor
NM_032501.4 NP_115890.2 acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 1 precursor

ACSS1 蛋白结构

AMP-binding

AMP-binding: AMP-binding enzyme (116 - 556)

AMP-binding_C

AMP-binding_C: AMP-binding enzyme C-terminal domain (564 - 642)

  • 0
  • 200
  • 400
  • 600
  • 689 a.a.
蛋白主名 其他名称

acetyl-coenzyme A synthetase 2-like, mitochondrial

acetate--CoA ligase 2

重组 ACSS1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71851 ACSS1 Protein, Human (P.pastoris, His) Q9NUB1-1 (A38-K689) ≥95%

关联疾病

疾病名称 别名
Cardiomyopathy, Infantile Histiocytoid

Histiocytoid Cardiomyopathy

Foamy Myocardial Transformation Of Infancy

Infantile Histiocytoid Cardiomyopathy

Infantile Xanthomatous Cardiomyopathy

Oncocytic Cardiomyopathy

Cardiomyopathy, Infantile Xanthomatous

Cardiomyopathy, Focal Lipid

Cardiomyopathy, Oncocytic

Focal Lipid Cardiomyopathy

Infantile Cardiomyopathy With Histiocytoid Change

CMIH

Cardiomyopathy Focal Lipid

Cardiomyopathy Infantile Xanthomatous

Cardiomyopathy Oncocytic
Canavan Disease

Aspartoacylase Deficiency

Aminoacylase 2 Deficiency

Spongy Degeneration Of Central Nervous System

Aspa Deficiency

Acy2 Deficiency

Canavan-Van Bogaert-Bertrand Disease

Mild Canavan Disease

Asp Deficiency

Spongy Degeneration Of The Central Nervous System

Severe Canavan Disease

Von Bogaert-Bertrand Disease

Canavan'S Disease

Spongy Degeneration Of The Brain

Juvenile Canavan Disease

Infantile Canavan Disease

Neonatal Canavan Disease

CAND

Disease, Canavan

Canavan Disease, Juvenile

Canavan Disease, Infantile

Canavan Disease, Neonatal
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-145953 VY-3-135 Inhibitor 98.51% 否
HY-RS00210 ACSS1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ACSS1 RGD RGD:1306246
Macaca mulatta ACSS1 VGNC VGNC:69416
Canis familiaris ACSS1 VGNC VGNC:52863
Bos taurus ACSS1 VGNC VGNC:25570
Mus musculus ACSS1 MGD MGI:1915988
Felis catus ACSS1 VGNC VGNC:82636
Others ACSS1 NCBI
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