RNASE7 - ribonuclease A family member 7 Gene

中文名称：核糖核酸酶 A 家族成员 7

种属: Homo sapiens

同用名: RAE1

基因 ID: 84659 | 基因类型: protein coding

关于 RNASE7

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:21,042,362-21,044,233 (from NCBI)

This gene has 2 transcripts (splice variants), 36 orthologues and 12 paralogues. Biased expression in esophagus (RPKM 35.9), skin (RPKM 11.5) and 1 other tissue.

功能概要

该基因编码的蛋白质属于胰腺核糖核酸酶家族，是核糖核酸酶 A 超家族的一个子集。该蛋白对细菌和真菌具有广谱抗菌活性。[RefSeq 提供，2014 年 10 月]

The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]

RNASE7 基因产物(1)

mRNA	Protein	Name
NM_032572.4	NP_115961.3	ribonuclease 7 precursor

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables RNA nuclease activity	IDA IDA: 通过直接分析推断	12244054	GOA
enables lipopolysaccharide binding	IDA IDA: 通过直接分析推断	20180804	GOA
enables peptidoglycan binding	IDA IDA: 通过直接分析推断	20180804	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	28514442	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in antibacterial humoral response	IDA IDA: 通过直接分析推断	25075772	GOA
involved in antimicrobial humoral immune response mediated by antimicrobial peptide	IDA IDA: 通过直接分析推断	12244054	GOA
involved in cytolysis in another organism	IDA IDA: 通过直接分析推断	20180804	GOA
involved in defense response to Gram-negative bacterium	IDA IDA: 通过直接分析推断	12244054	GOA
involved in defense response to Gram-positive bacterium	IDA IDA: 通过直接分析推断	12244054	GOA
involved in defense response to fungus	IDA IDA: 通过直接分析推断	12244054	GOA
involved in innate immune response	IDA IDA: 通过直接分析推断	16940129	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	25075772	GOA
located in extracellular region	IDA IDA: 通过直接分析推断	19641608	GOA
located in extracellular space	IDA IDA: 通过直接分析推断	25075772	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RNASE7 蛋白结构

RnaseA

0
100
156 a.a.

蛋白主名

其他名称

ribonuclease 7

RNase 7

关联疾病

疾病名称

别名

Psoriasis

Superficial Mycosis

Piedra

Steroid-Modified Tinea Infection

Pityriasis Versicolor

Tinea Versicolor

Infection By Pityrosporum Furfur

Tinea Pedis

Athlete'S Foot	Dermatophytosis Of Foot
Ringworm Of Foot	Moccasin Foot

Tinea Corporis

Dermatophytosis Of The Body

Dermatophytosis Of The Trunk

Chronic Pyelonephritis

Acute Pyelonephritis

Apn - [Acute Pyelonephritis]

Dermatophytosis

Tinea	Dermatophytosis, Unspecified
Ringworm	Infections Due To Species Of Epidermophyton, Microsporum And Trichophyton
Cutaneous Mycosis	Dermal Mycosis
Superficial Mycosis, Unspecified	Fungus Infection Of Skin
Skin Mycosis	Dermatitis Fungoid
Fungal Dermatitis	Fungal Dermatosis
Mycotic Infection Of Skin

Tinea Cruris

Dermatophytosis Of Groin & Perianal Area	Dermatophytosis Of Groin And Perianal Area
Dhobie Itch	Tinea Of Perianal Region

Pyelitis

Dermatitis, Atopic

Atopic Dermatitis	Atopic Eczema
Dermatitis, Atopic, Susceptibility To, 1	Atod
Eczema, Atopic	Dermatitis, Atopic 1
Allergic Dermatitis	Atopic Neurodermatitis
Besnier'S Prurigo	Dermatitis, Atopic, 1
Dermatitis Atopic	Eczema
Besnier Prurigo

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RNASE7 - ribonuclease A family member 7 Gene

关于 RNASE7

功能概要

RNASE7 基因产物(1)

RNASE7 蛋白结构

关联疾病

热门区域

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RNASE7 - ribonuclease A family member 7 Gene

关于 RNASE7

功能概要

RNASE7 基因产物(1)

RNASE7 蛋白结构

关联疾病

相关产品

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z