2. Anti-infection
  3. Influenza Virus
  4. Influenza virus-IN-1

Influenza virus-IN-1 (compound 14) 是一种有效的 甲型流感病毒 抑制剂，EC50 为 2.46 µM, CC< sub>50 的 >200 µM。Influenza virus-IN-1 对 PAN 核酸内切酶具有浓度依赖性抑制活性，EC50 为 312.36 nM。Influenza virus-IN-1 显示出抗甲型流感病毒活性。

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Influenza virus-IN-1 Chemical Structure

Influenza virus-IN-1 Chemical Structure

CAS No. : 108729-21-1

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Influenza virus-IN-1 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Influenza virus-IN-1 (compound 14) is a potent influenza A virus inhibitor with an EC50 of 2.46 µM and CC50 of >200 µM. Influenza virus-IN-1 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 312.36 nM. Influenza virus-IN-1 shows shows anti-influenza A virus activities[1].

IC50 & Target

EC50: 2.46 µM (influenza virus); CC50: >200 µM (influenza virus)[1]
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
MDCK CC50
> 200 μM
Compound: 14
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 31954881]
分子量

303.31

Formula

C16H17NO5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Influenza virus-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Influenza virus-IN-1108729-21-1Influenza VirusMDCK cellsanti-IAV activityPAN endonucleaseInhibitorinhibitorinhibit

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