2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. J 104129 fumarate

J 104129 fumarate 是一种选择性具有口服活性的 muscarinic M3 拮抗剂，对于 M3、M2 的 Ki 值分别为 4.2 nM 和 490 nM。J 104129 fumarate 拮抗乙酰胆碱诱导的支气管收缩。J 104129 fumarate 具有研究阻塞性气道疾病的潜力。

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J 104129 fumarate Chemical Structure

J 104129 fumarate Chemical Structure

CAS No. : 257603-40-0

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规格 价格 是否有货 数量
1 mg ￥2000
4 - 5 周
5 mg ￥5030
4 - 5 周
10 mg 现货 4 - 5 周
50 mg   询价  
100 mg   询价  

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Customer Review

Other Forms of J 104129 fumarate:

J 104129 fumarate 相关抗体

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mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

J 104129 fumarate is a selective and orally active muscarinic M3 antagonist with Ki values of 4.2 nM and 490 nM for M3 and M2, respectively. J 104129 fumarate antagonized ACh-induced bronchoconstriction. J 104129 fumarate has the potential for the research of obstructive airway disease[1].

IC50 & Target[1]

mAChR3

4.2 nM (Ki)

mAChR2

490 nM (Ki)

分子量

500.63

Formula

C28H40N2O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

J 104129 fumarate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

J 104129257603-40-0J104129J-104129mAChRMuscarinic acetylcholine receptorbronchoconstrictionobstructive airwayInhibitorinhibitorinhibit

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产品名称：
J 104129 fumarate
目录号：
HY-107653
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