2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. JN403

JN403 是一种具有口服活性的 α7 烟碱乙酰胆碱受体 (α7 nicotinic acetylcholine receptor) 选择性激动剂。JN403 可用于中枢神经系统疾病的研究。

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JN403 Chemical Structure

JN403 Chemical Structure

CAS No. : 942606-12-4

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JN403 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

JN403 is an orally active and selective α7 nicotinic acetylcholine receptor agonist. JN403 can be used in the study of central nervous system disorders[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
GH3 EC50
100 nM
Compound: 30, JN403
Agonist activity at human recombinant alpha7 nAChR expressed in human GH3 cells by calcium flux assay
Agonist activity at human recombinant alpha7 nAChR expressed in human GH3 cells by calcium flux assay
[PMID: 21919481]
分子量

292.35

Formula

C16H21FN2O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

JN403 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JN403942606-12-4JN 403JN-403nAChRNicotinic acetylcholine receptorsα7 nicotinic acetylcholine receptornAChR alpha7Inhibitorinhibitorinhibit

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目录号：
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