2. Anti-infection
  3. Influenza Virus
  4. Laninamivir octanoate hydrate

Laninamivir octanoate hydrate  (Synonyms: CS-8958 hydrate)

目录号: HY-14818C
产品使用指南

摩尔计算器

Laninamivir octanoate hydrate (CS-8958 hydrate)，Laninamivir 的前药，是一种长效的神经氨酸酶 (neuraminidase, NA) 抑制剂，具有抗流感病毒活性。Laninamivir octanoate hydrate 对耐 Oseltamivir 的病毒以及对大流行性流感病毒均具有抗流感活性。

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Laninamivir octanoate hydrate Chemical Structure

Laninamivir octanoate hydrate Chemical Structure

CAS No. : 1233643-88-3

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Laninamivir octanoate hydrate 的其他形式现货产品:

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Other Forms of Laninamivir octanoate hydrate:

Laninamivir octanoate hydrate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Laninamivir octanoate hydrate (CS-8958 hydrate), a prodrug of Laninamivir, is a long-acting neuraminidase (NA) inhibitor with anti-influenza virus activity. Laninamivir octanoate hydrate shows anti-influenza activity against Oseltamivir-resistant viruses, and also against the pandemic influenza viruses[1][2].

体外研究
(In Vitro)

Laninamivir octanoate (CS-8958) 对 H1N1 病毒株、H3N2 病毒株和 H2N2 (A/Singapore/1/57) 病毒株具有抑菌活性，IC50 分别为 631-1170 nM、39.2-221 nM 和 128 nM [1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Laninamivir octanoate hydrate 相关抗体:
体内研究
(In Vivo)

Laninamivir octanoate (CS-8958；95μg/kg；鼻内的管理；3 次) 在感染前 4 h、感染后 4 h 和 17 h 处理，在小鼠感染模型中均有明显的延长寿命效果[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female BALB/c mice (5-6 weeks old) infected with influenza A virus A/PR/8/34[1]
Dosage: 0.2 μmol/kg (95 μg/kg)
Administration: Intranasal administration; three dose; at 4 h before and 4 h and 17 h postinfection
Result: Showed life-prolonging effect in infected model.
Clinical Trial
分子量

490.55

Formula

C21H38N4O9
CAS 号
中文名称

辛酸拉尼米韦水合物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Laninamivir octanoate hydrate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Laninamivir octanoate1233643-88-3CS-8958辛酸拉尼米韦水合物CS8958CS 8958Influenza VirusAnti-influenzaneuraminidaseH3N2H2N2inhaledInhibitorinhibitorinhibit

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