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  3. Lu AF11205

Lu AF11205 是一种mGlu5受体正变构调节剂,具有调节mGlu5受体活性的活性。Lu AF11205的优化可得到一系列强效的融合噻唑类似物,其结构和活性受取代基影响,在mGlu5受体表达的细胞系中可影响受体功能。

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Lu AF11205 Chemical Structure

Lu AF11205 Chemical Structure

CAS No. : 1290133-16-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors.

分子量

296.39

Formula

C17H16N2OS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Lu AF11205 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Lu AF11205
目录号:
HY-117697
需求量: