2. GPCR/G Protein
  3. GLP Receptor
  4. Maridebart cafraglutide

Maridebart cafraglutide  (Synonyms: AMG 133)

目录号: HY-164535
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摩尔计算器

Maridebart cafraglutide (AMG 133) 是一种抗体-肽结合物，作为 GLP-1 受体激动剂和 GIP 受体拮抗剂。Maridebart cafraglutide 可以在雄性肥胖小鼠和猕猴中减轻体重并改善代谢指标。Maridebart cafraglutide 有望用于肥胖的研究。

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Maridebart cafraglutide Chemical Structure

Maridebart cafraglutide Chemical Structure

CAS No. : 2887445-76-1

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Maridebart cafraglutide 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Maridebart cafraglutide (AMG 133) is an antibody-peptide conjugate acting as a GLP-1 receptor agonist and an antagonist of the GIP receptor. Maridebart cafraglutide reduces body weight and improve metabolic markers in male obese mice and cynomolgus monkeys. Maridebart cafraglutide is promising for research of obesity[1][2].

分子量

153,514 (average)

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Maridebart cafraglutide 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Maridebart cafraglutide2887445-76-1AMG 133AMG133AMG-133GLP Receptorantibody-peptide conjugateGLP-1GIPbody weightmetabolic markersmicecynomolgus monkeysobesityInhibitorinhibitorinhibit

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