2. Academic Validation
  3. Guaiane-type sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric oxide production

Guaiane-type sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric oxide production

  • J Asian Nat Prod Res. 2009 Aug;11(8):737-47. doi: 10.1080/10286020903042358.
Yan Lou 1,  Feng Zhao,  Hao He,  Kai-Feng Peng,  Xiao-Hua Zhou,  Li-Xia Chen,  Feng Qiu
Affiliations

Affiliation

  • 1 Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
PMID: 20183317 DOI: 10.1080/10286020903042358
Abstract

Four new guaiane-type Sesquiterpenes (1S,4S,5S,10R)-zedoarondiol, zedoalactones D, E, and F (1-4), along with 10 known ones (5-14), were isolated from Curcuma wenyujin Y.H. Chen et C. Ling. The structures of these new compounds were elucidated by spectroscopic methods. The inhibitory effects of compounds 1-14 on nitric oxide production in lipopolysaccharide-activated macrophages were evaluated.

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