2. Academic Validation
  3. Two new alkaloids from Melodinus suaveolens

Two new alkaloids from Melodinus suaveolens

  • Nat Prod Commun. 2014 Oct;9(10):1445-7.
Fan Lu,  Pan Liu,  Shan-Shan Yin,  Jun Zhang,  Jing Wang
PMID: 25522534
Abstract

Two new Melodinus-type Alkaloids, 15β-hydroxy-14,15-dihydroscandine (1) and 14,15-dihydroscandine (2), together with 6 known ones were isolated from Melodinus suaveolens. The structures of the new compounds were identified from spectroscopic (NMR, UV, IR, CD) and mass spectrometric data and Mosher's method. The new compounds exhibited significant, dose-dependent inhibition of the production of lipopolysaccharide (LPS)-induced NO, IL-6 and IL-8 in mice macrophages.

Figures
Products
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z